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Seogho Son

As seen in: Science Magazine, BioRxiv, Cell Press
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Articles

CXCL1-CXCR2 signaling mediates cancer cell growth and response to radiation therapy in leptomeningeal metastasis

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By Mitra P. Maz, Yuli Chen, Shajila Siricilla, Ahmed Osman, Ján Remšík, Jenna Snyder, Seogho Son, Ana Rita Nobre, Morgan E. Freret, Kiana Chabot, Xinran Tong, Helen Y. Wang, Min Li, Marisa Rose, Andrew Dunbar, Ross Levine, Jonathan T. Yang, Adrienne Boire, Francis Y. He, Sophia Toomey, Rachel Estrera, Neil Ari Wijetunga, Branavan Manoranjan, David Guber, Sofia Piedrafita-Ortiz
| Science Magazine Verified
Abstract Supplementary Materials REFERENCES AND NOTES Information & Authors Metrics & Citations Check Access References Figures Tables Media Share This article has 0 eLetter . Abstract Leptomeningeal metastasis (LM) is a fatal neurological complication of cancer. Proton craniospinal irradiation (pCSI) has emerged as a promising life-prolonging intervention for patients with LM, but response to this treatment varies. Here, we aimed to characterize the molecular basis of pCSI resistance and response.
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S-nitrosylation-triggered unfolded protein response maintains hematopoietic progenitors in Drosophila

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By Bumsik Cho, Mingyu Shin, Eunji Chang, Seogho Son
| Cell Press Verified
• None Drosophila as a Model to Study Cellular Communication Between the Hematopoietic Niche and Blood Progenitors Under Homeostatic Conditions and in Response to an Immune Stress. 719349 • None The spitz gene is required for photoreceptor determination in the Drosophila eye where it interacts with the EGF receptor. : • None ER Stress Induces Cell Cycle Arrest at the G2/M Phase Through eIF2α Phosphorylation and GADD45α.
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S-nitrosylation-mediated unfolded protein response maintains hematopoietic progenitors

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By Bumsik Cho, Mingyu Shin, Eunji Chang, Seogho Son
| BioRxiv
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