Shakiba Ardestani

Le carcinome séreux de l’ovaire de degré élevé (CSODE) de malignité est la forme la plus répandue et la plus mortelle des cancers de l’ovaire, et affecte 1 femme sur 701,2 Il n’existe pas de test de dépistage efficace du CSODE, et les personnes consultent souvent lorsque la maladie est déjà à un stade avancé. De 70 %–80 % des morts par cancer de l’ovaire sont dues au CSODE1.

High-grade serous ovarian cancer (HGSOC) is the most common and most fatal form of ovarian cancer, affecting 1 in 70 females1,2 No effective screening test is available for HGSOC, and patients often present in an advanced stage of disease. Around 70%–80% of deaths from ovarian cancer are caused by HGSOC.1 High-grade serous ovarian cancer originates in the fimbria of the fallopian tube3 This cancer develops via a stepwise progression within the distal fallopian tube epithelium.

Postcoital bleeding is a distressing symptom that affects 0.7%–9% of patients1,2 Poistcoital bleeding is nonmenstrual bleeding that occurs after penetrative intercourse and often coexists with intermenstrual bleeding.1,3 Cervical ectropion (19%–34%), cervical or endometrial polyps (5%–18%), infection (e.g., vaginitis, cervicitis), pregnancy and trauma are common causes in premenopausal patients, and atrophy is a common cause after menopause (Appendix 1, available at...