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Shaoyin Chen on Muck Rack

Shaoyin Chen

As seen in: The Journal of Biological Chemistry
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Articles

Binding of DEAD-box helicase Dhh1 to the 5′-untranslated region of ASH1 mRNA represses localized translation of ASH1 in yeast cells

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By Qianjun Zhang, Xiuhua Meng, Delin Li, Shaoyin Chen
| The Journal of Biological Chemistry Verified
Local translation of specific mRNAs is regulated by dynamic changes in their subcellular localization, and these changes are due to complex mechanisms controlling cytoplasmic mRNA transport. The budding yeast Saccharomyces cerevisiae is well suited to studying these mechanisms because many of its transcripts are transported from the mother cell to the budding daughter cell. Here, we investigated the translational control of ASH1 mRNA after transport and localization.
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