1 Introduction Sensorineural hearing loss (SNHL), the predominant type of hearing loss worldwide, arises primarily from factors such as noise exposure, ototoxic drugs, infections, age-related degeneration, and hereditary mutations. Aminoglycoside antibiotics, such as neomycin, gentamicin, streptomycin, and kanamycin, constitute a class of broad-spectrum antibiotics widely employed in clinical practice for the treatment of infections caused by Gram-negative pathogens.