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Shayin V. Gibson on Muck Rack

Shayin V. Gibson

As seen in: Cell Press
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Articles

Everybody needs good neighbours: the progressive DCIS microenvironment

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By Shayin V. Gibson, Reza Roozitalab, Michael Allen, J. Jones
| Cell Press Verified
Highlights Identifying predictors of recurrence and invasive progression of ductal carcinoma in situ (DCIS) is a major clinical challenge. Changes to the local microenvironment, rather than the neoplastic cells, are major contributors to progression. The transition of DCIS to invasive ductal carcinoma (IDC) requires cumulative changes to the stroma to promote a tumour-permissive niche that facilitates local invasion.
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Tumour microenvironment 3D-modelling: simplicity to complexity and back again

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By Edward Carter, Reza Roozitalab, Shayin V. Gibson, Richard P. Grose
| Cell Press Verified
Place A.E. et al. The microenvironment in breast cancer progression: biology and implications for treatment. Breast Cancer Res. 2011; 13: 227 Ho W.J. et al. The tumour microenvironment in pancreatic cancer - clinical challenges and opportunities. Nat. Rev. Clin. Oncol. 2020; 17: 527-540 Rodrigues J. et al. 3D in vitro model (r)evolution: unveiling tumor-stroma interactions. Trends Cancer. 2021; 7: 249-264 Ahuja D. et al. SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation.
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