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A CEBPB-IPO4-FASN-MAVS axis limits innate immune activation and viral pneumonia
Virus infection For cell infection experiments, cells were seeded into designated culture plates or dishes. Upon reaching approximately 90% confluency, the cells were washed with phosphate-buffered saline (PBS) and incubated with serum-free medium containing SARS-CoV-2 trVLP, PR8, VSV/VSV-GFP, SeV, RSV, or HSV-1 at the indicated multiplicities of infection. After 1–2 h, the inoculum was replaced with serum-containing medium or virus isolation medium supplemented with TPCK for further culture.
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