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Sheula Barlow on Muck Rack

Sheula Barlow

As seen in: Archives of Disease in Childhood
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Articles

An open-label, phase IV randomised controlled trial of two schedules of a four-component meningococcal B vaccine in UK preterm infants

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By Anna Calvert, Nick Andrews, Ray Borrow, Sheula Barlow
| Archives of Disease in Childhood Verified
Discussion We found that both 2+1 and 3+1 schedules for 4CMenB were immunogenic in preterm infants, although the GMT against strain NZ98/254 (PorA) at 12 months, and the proportions of infants with postprimary and prebooster SBA titres ≥4 were significantly higher with the 3+1 than 2+1 schedule. The vaccine antigen PorA is the immunodominant component of outer membrane vesicle (OMV) vaccines.
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