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Shonna M. McBride on Muck Rack

Shonna M. McBride

Atlanta
As seen in: BioRxiv, Cell Press
Assoc Prof at Emory University. microbiology, genetics, antibiotic resistance and C. diff. Opinions are my own. she/her #Cajun #FirstgenSTEM #Cdiff
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Articles

The predicted acetoin dehydrogenase pathway represses sporulation of Clostridioides difficile

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By Daniela Wetzel, Arshad Rizvi, Adrianne N. Edwards, Shonna M. McBride
| BioRxiv
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Strain-Dependent RstA Regulation of Clostridioides difficile Toxin Production and Sporulation

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By Adrianne N. Edwards, Ellen G. Krall, Shonna M. McBride
| asm.org
Research Article Adrianne N. Edwards, Ellen G. Krall, Shonna M. McBride Michael J. Federle, Editor DOI: 10.1128/JB.00586-19 ABSTRACT The anaerobic spore former Clostridioides difficile causes significant diarrheal disease in humans and other mammals. Infection begins with the ingestion of dormant spores, which subsequently germinate within the host gastrointestinal tract. There, the vegetative cells proliferate and secrete two exotoxins, TcdA and TcdB, which cause disease symptoms.
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The impact of pH on Clostridioides difficile sporulation and physiology

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By Shonna M. McBride, Daniela Wetzel
| asm.org
Physiology Daniela Wetzel, Shonna M. McBride DOI: 10.1128/AEM.02706-19 ABSTRACT Clostridioides difficile is a pathogenic bacterium that infects the human colon to cause diarrheal disease. Growth of the bacterium is known to be dependent on certain bile acids, oxygen levels and nutrient availability in the intestine, but how the environmental pH can influence C. difficile is mostly unknown. Previous studies indicated that C.
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