Shreshth Shekhar on Muck Rack

Shreshth Shekhar

As seen in: Biological Psychiatry
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Articles

A Novel Mouse Model of Parkinson's Disease for Investigating Progressive Pathology and Neuroprotection

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By Shreshth Shekhar, Sathyapriya Senthil, Santhosh Kumar Subramanya, Devu B Kumar
| biorxiv.org
Abstract Developing animal models that successfully recapitulate the features of progressive Parkinson′s disease (PD) is crucial for understanding disease progression mechanisms and creating effective therapeutic interventions. In this study, we created a mouse model of PD by overexpressing α-synuclein through a combined injection of AAV6-α-synuclein and preformed fibrils (PFFs) into the medial and lateral substantia nigra (SN).
Open in Who Shared Issue with article?

Posterior Cerebellar Resting-State Functional Hypoconnectivity: A Neural Marker of Schizophrenia across Different Stages of Treatment Response

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By Neelabja Roy, Rose Dawn Bharath, Dhruva Ithal, Shreshth Shekhar
| Biological Psychiatry
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