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Human carbonic anhydrase modulators: the past, present, and future
Section snippets hCAs and their multiple pharmacologic applications The physiological roles of the metalloenzymes hCAs are well recognized and were intensively investigated as pharmacological drug targets over the last seven decades [1., 2., 3., 4., 5.]. hCAs represent a class of drug targets with multiple isoforms that exhibit diverse cellular localizations and physiological functions, often differing significantly between tissues and clinical conditions (Box 1) [1., 2., 3., 4., 5., 6.].
Screening Natural Cholesterol Analogs to Assemble Self‐Adjuvant Lipid Nanoparticles for Antigens Tagging Guided Therapeutic Tumor Vaccine
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adma202419182-sup-0001-SuppMat.docx12.6 MB Supporting Information References 1a) , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , et al., Nature 2023, 618, 144; b) , , , , , , , , , , , , , , , , , , Sci. Transl. Med. 2023, 15, abn3464; c) , , , , , , Sci. Adv. 2022, 8, adc8738; d) , , , , Adv. Mater. 2023, 35, 2303261.
A novel topological indium-organic framework for reversible ammonia uptake under mild conditions and catalysis
A novel topological indium-organic framework for reversible ammonia uptake under mild conditions and catalysis As a new generation of porous materials, metal-organic frameworks (MOFs) are the promising candidates for NH3 uptake. However, to obtain the stable MOFs for a good NH3 adsorption capacity and reliable recyclability under mild conditions remains a big challenge.
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