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Shuying He on Muck Rack

Shuying He

As seen in: Nature, MDPI, Taylor & Francis Online, ACS Publications, Royal Society of Chemistry, BioRxiv, Dove Medical Press, Genes and Development Journal
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Articles

Lactobacillus johnsonii Alleviates Immune Checkpoint Inhibitor-Associated Colitis by Modulating Macrophage Polarization, Th1/Treg Cell Balance, and Intestinal Barrier Function via the Tryptophan Metabolism-AhR Pathway Click to copy article link Article li

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By Wei Liang, Shuying He, Heqing Tao
| ACS Publications
1. Introduction Click to copy section linkSection link copied! Immune checkpoint inhibitors (ICIs) have demonstrated promising efficacy across a range of tumors, (1) driving their growing adoption in clinical practice. However, alongside their therapeutic benefits, ICIs can trigger immune-related adverse events (irAEs) as a result of excessive immune system activation. These adverse events may involve multiple organs, including the skin, gastrointestinal tract, liver, and lungs.
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Engineered Ti₃C₂ MXene nanosystems for macrophage-targeted therapy of metabolic dysfunction-associated steatohepatitis

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By Shuying He, Jingnan Qiu, Runhua Li, Shuyun Wu, Wei Liang, Kequan Chen, Liang Peng
| Nature Verified
Abstract Macrophages are central to the pathogenesis of metabolic dysfunction-associated steatohepatitis (MASH), a condition driven by persistent inflammation and elevated reactive oxygen species (ROS). Nanotherapeutic strategies that simultaneously suppress inflammation and eliminate ROS thus hold significant promise. Here, we engineered mannose-modified trimethyl chitosan-coated Ti₃C₂ MXene nanozymes (MMCT) for selective targeting of hepatic macrophages via mannose receptor-mediated endocytosis.
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Surface-Engineered Titanium Carbide MXenzyme Boosts ROS-Scavenging and Anti-Inflammation Activities for Inflammatory Bowel Disease Click to copy article link Article link copied!

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By Shuying He, Jingnan Qiu, Heqing Tao
| dx.doi.org
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