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Si-Ying Xiang

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Articles

MICUs protect the heart by regulating mitochondrial calcium

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By Jian-Hua Chen, Emily J Mellen, Brent P. Forester, Si-Ying Xiang
| ScienceDirect Verified
Regulation of mitochondrial calcium uptake by the mitochondrial calcium uniporter (mtCU) complex is crucial for heart function. In a recent study, demonstrated that mitochondrial calcium uptake (MICU)1 and MICU2, regulatory subunits of the complex, help maintain calcium homeostasis in cardiac mitochondria, providing potential targets for therapies aimed at improving mitochondrial function in heart disease. Calcium (see Glossary) keeps us alive.
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