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Siddappa N. Byrareddy on Muck Rack

Siddappa N. Byrareddy

As seen in: National Institutes of Health, Color Research & Application, Nature, Wiley, Wiley Online Library, Frontiers, MDPI, BioRxiv, The Lancet, Scripps News and
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Articles

In-Vitro Evaluation of HIV/SARS-CoV-2 Co-Infection Mediated Proteomic Changes in Astrocytes and Pericytes Reveals Altered Signaling Pathways Associated With Neurodegenerative Disorders

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By Siddappa N. Byrareddy, Arpan Acharya, Experimental Neuroscience
| Wiley Online Library Verified
ACE2 Angiotensin converting enzyme 2 AD Alzheimer's Disease ALS Amyotrophic lateral sclerosis Aβ Amyloid-β BBB Blood-Brain Barrier CNS Central nervous system COVID-19 Coronavirus disease of 2019 EMEM Eagle's Minimum Essential Medium HAND HIV-Associated Neurocognitive Disorder HD Huntington Disease HIV Human immunodeficiency virus IL-1β Interleukin 1 beta IL-18 Interleukin 18 IL-6 Interleukin 6 MDM Monocyte-derived macrophages MERS-CoV Middle East respiratory syndrome coronavirus MOI...
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Neurovirulent and non-neurovirulent strains of HIV-1 and their Tat proteins induce differential cytokine-chemokine profiles

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By Siddappa N. Byrareddy, Milka Rodriguez, Udaykumar Ranga, Vasudev R Rao
| BioRxiv
Abstract HIV-1 enters the central nervous system (CNS) early in infection, and a significant proportion of people with HIV experience CNS complications despite anti-retroviral therapy. Chronic immune dysfunction, inflammatory cytokines and chemokines, and viral proteins like Tat and gp120 released by HIV-1-infected immune cells are implicated in the pathogenesis of HIV-1-associated neurocognitive disorders (HAND).
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Design of novel and highly selective SARS-CoV-2 main protease inhibitors

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By Siddappa N. Byrareddy, Byrareddy SN
| ASM Journals
INTRODUCTION Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a global pandemic in 2020 which continues to inflict substantial morbidity and mortality worldwide. As of February 2024, over 775 million SARS-CoV-2 cases, resulting in over 7.0 million deaths worldwide, were reported to the World Health Organization.
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