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Sidhartha R. Sinha on Muck Rack

Sidhartha R. Sinha

As seen in: Nature, Cell Press, Cell Reports Medicine, HCP Live, Gastroenterology, Gastrointestinal Endoscopy
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Articles

Mo1599 FASTING-MIMICKING DIET MODIFIES GUT MICROBIAL AND METABOLITE PROFILES AND IDENTIFIES MICROBIAL PREDICTORS OF RESPONSE IN CROHN’S DISEASE

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By Eliza Dickson, John Mark Gubatan, Mark Davis, Jiayu Ye, Meng Sun, Touran Fardeen, Laren Becker, Mark Davis, Justin L. Sonnenburg, Christopher Gardner, Sidhartha R. Sinha, Amoolya Chandrabhatta
| Gastrointestinal Endoscopy Verified
Also available on ScienceDirect
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Multi-omics reveal vitamin D regulation of immune-gut microbiome interactions and tolerogenic pathways in inflammatory bowel disease

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By John Mark Gubatan, Jiayu Ye, Theresa L. Boye, Jacqueline Hoang, Touran Fardeen, Michelle Temby, Sean P Spencer, Prasanti Kotagiri, Michael Rosen, Ole Nielsen, Scott Boyd, Justin L. Sonnenburg, Sidhartha R. Sinha, Raoul S. Sojwal, Samuel J.S. Rubin, Stephan Rogalla
| Cell Reports Medicine Verified
Forty-eight patients with IBD completed the clinical trial and provided a full set of pre- and post-vitamin D treatment blood and stool samples (study schematic summarized in Figure 1A) and are included in the final analysis. Table 1 summarizes the baseline clinical characteristics of patients in the clinical trial. The mean age of patients was 38.96 years, and 45.8% were male and 54.2% were female. About 56.3% of patients had ulcerative colitis (UC), whereas 43.7% had Crohn disease (CD).
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Microplastics and nanoplastics in the human gut: from signals to standards - Nature Reviews Gastroenterology & Hepatology

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By Brian Deng, Sidhartha R. Sinha, Gavin Lear, Carolina Tropini
| Nature Verified
The gastrointestinal tract is a critical interface for microplastic and nanoplastic exposure, yet causal links to health outcomes remain uncertain. We outline current methodological challenges and provide a list of minimum standards for rigorous study design, standardized reporting and careful attention to interpretations to distinguish mechanism from signals.
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