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Siying Liu on Muck Rack

Siying Liu

As seen in: Color Research & Application, Nature, Wiley Online Library, Frontiers, Frontiers in Marine Science, MDPI, ACS Publications, Royal Society of Chemistry, BioRxiv, Canadian Journal of Infectious Diseases & Medical Microbiology and
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Articles

Rheum, Scutellaria, and Houttuynia effervescent tablets: a green strategy for controlling Vibrio parahaemolyticus outbreaks in aquaculture

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By Ning WANG, Zhenyuan Wu, Siying Liu, Ziheng Calvin Xu, Hong Jiang, Hongjun Wang
| Frontiers in Marine Science
Abstract Objective: The widespread misuse of antibiotics in aquaculture has led to severe drug resistance, threatening both industry sustainability and food safety. With increasing restrictions on antibiotic use, plant-derived antimicrobials have emerged as eco-friendly alternatives.
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Covalent allosteric inhibition of AARS1 lactyltransferase

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By Yunyuan Huang, Siying Liu, Luyang Tian, Yang Tang, Yilin Dou, Huiling Wang, Tao Zheng, Mingyang Wang, Runhao Li, Zhi Jian Wang, Zhaocai Zhou, Xin McRae Chen, Jinrong Min
| Nature Verified
Abstract Alanyl-tRNA synthetase 1 (AARS1) was recently identified as a lactyltransferase responsible for protein lactylation, a modification associated with epigenetic regulation and metabolic adaptation. Here, we report compound XY353, which covalently binds C184 of AARS1, inducing steric clashes with F175 and triggering structural rearrangements in the region that displace W176, a key residue for lactate binding.
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Upper-ocean stratification changes control ENSO amplitude shift under sustained global warming - Nature Communications

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By Rong-Hua Zhang, Maonan Chen, Lu Zhou, Hai Zhi, Siying Liu, Lingjiang Tao, Minmin Wu, Jiaxiang Gao, Hongna Wang
| Nature Verified
Abstract As projected by climate models in the high emission scenarios, the El Niño–Southern Oscillation (ENSO) exhibits a non-monotonic amplitude shift. However, its key drivers remain poorly quantified. Here we introduce a framework using an intermediate coupled model (ICM) that coherently represents mean-state oceanic climatologies in the tropical Pacific, derived from eight selected climate models across three periods (1940–1990, 2040–2090 and 2240–2290).
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