Siying Wang
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A literature-informed Delphi framework for pediatric medication science books
Abstract Objective: To construct a quantifiable indicator system for evaluating pediatric pharmacology knowledge and to provide a scientific basis for writing popular science books on pediatric medication. Methods: From June to July 2025, a systematic literature search was performed to conduct a general systematic review of pediatric medication science popularization content. Literature information was integrated via thematic synthesis to formulate a preliminary questionnaire.
Association of HER2, p53, and lymphovascular space invasion with lymph node metastasis in endometrial cancer: a retrospective cohort study
Abstract Background: The assessment of lymph node metastasis (LNM) in endometrial carcinoma is critical for optimizing the extent of surgical resection and formulating individualized therapies. This study aimed to investigate the associated factors of the LNM in endometrial carcinoma. Methods: 438 patients with endometrial carcinoma who underwent primary surgical staging between June 2014 and June 2025 were retrospectively analyzed.
A cell-state-centric view of inherited ESCC risk
Main text Genome-wide association studies (GWASs) have identified numerous susceptibility loci for esophageal squamous cell carcinoma (ESCC),2,3,4 highlighting an important contribution of inherited genetic variation to cancer risk. Yet for most of these loci, biological mechanisms linking genetic variation to tumor development remain unknown. Perhaps an even more important unanswered question is where risk variants exert their effects within the complex cellular ecosystem of ESCC.
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