Siyuan Yin
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In vivo CRISPR screens identify dual functions of DNMT3A in mediating tumor immune evasion
Abstract Cancer immunotherapy has achieved remarkable clinical efficacy across multiple cancers but remains ineffective for most patients, and the mechanisms underlying resistance remain incompletely understood. Here, we perform in vivo CRISPR-Cas9 screens in female mice and identify DNA methyltransferase 3 A (DNMT3A) as a key driver of tumor immune evasion through both methyltransferase-dependent and -independent mechanisms.
Comparative Study of Ce-MOF-Derived Mesoporous CeO 2 Architectures for Enhanced CO 2 Methanation over Ni/CeO 2 Catalysts Click to copy article link Article link copied!
Abstract Click to copy section linkSection link copied! Metal–organic frameworks (MOFs) are promising precursors for constructing high-performance catalysts due to their ordered porous architectures, high surface areas, and tunable compositions. In this work, mesoporous CeO2 supports derived from Ce-BTC, Ce-UiO-66, and Ce-BDC were prepared and used to construct 10 wt % Ni/CeO2 catalysts for CO2 methanation.
Does Climate Governance Affect ESG Performance in Traditional Energy Firms? Policy Evaluation and Mechanism Analysis
References , , and . 2024. “ESG Certification, Green Innovation, and Firm Value: A Quasi-Natural Experiment Based on SynTao Green Finance's ESG Ratings: A Pre-Registered Study.” Pacific-Basin Finance Journal 88: 102572. , and . 2018. “Corporate Social Responsibility and Investment Efficiency.” Journal of Business Ethics 148: 647–671. , , and . 2004. “How Much Should We Trust Differences-In-Differences Estimates?” Quarterly Journal of Economics 119, no. 1: 249–275. , and . 2021.
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