Soheil Akbari
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Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
AAV adeno-associated virus ATM ataxia telangiectasia mutated CBh adenovirus-associated hybrid promoter DM differentiation medium ECM extracellular matrix eHEPOs iPSC (endoderm)-derived human hepatic organoids EM expansion medium EMT epithelial-mesenchymal transition FDR false discovery rate FFA free fatty acids GFP green fluorescent protein GPC3 glypican-3 gRNAs guide RNAs GSEA gene set enrichment analysis HCC hepatocellular carcinoma HSCs hepatic stellate cells IHC immunohistochemical...
Biomedicines | Free Full-Text | Design of Alginate/Gelatin Hydrogels for Biomedical Applications: Fine-Tuning Osteogenesis in Dental Pulp Stem Cells While Preserving Other Cell Behaviors
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Enhancing Osteogenic Potential in Bone Tissue Engineering: Optimizing Pore Size in Alginate-Gelatin Composite Hydrogels
1 Introduction Bone tissue engineering is a rapidly expanding field of research aiming to develop innovative solutions for regenerating and repairing damaged bone tissues.[1] In this context, biomaterials play a crucial role as a structural support to guide cell growth and differentiation.[1, 2] Among these biomaterials, alginate–gelatin (Alg–Gel) hydrogels are emerging as promising candidates for bone tissue engineering.[3, 4] Alginate, a biopolymer derived from marine algae, and gelatin, a...
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