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Sonja M. Wojcik on Muck Rack

Sonja M. Wojcik

As seen in: Science Magazine, BioRxiv
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Articles

Munc13-1 couples DAG and Ca2+ signaling to dynamic vesicle priming, synaptic short-term plasticity, and posttetanic potentiation

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By Kapil Sirohi, Hao Jia, Yanling Lv, Mrinalini Ranjan, Kun-Han Lin, Brian Mueller Verified, Sonja M. Wojcik, Mareike Lohse, Thomas C. Südhof, Erik Jorgensen, Erwin Neher, Noa Lipstein, Nils Brose, Holger Taschenberger
| Science Magazine Verified
Abstract Synaptic strength and plasticity are fine-tuned by neuromodulation and use-dependent second-messenger signaling. Presynaptic diacylglycerol (DAG), Ca2+, and Ca2+-calmodulin signaling converge on the essential synaptic vesicle (SV) priming protein Munc13-1 via its regulatory C1, C2B, and CaM-binding domains.
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Transcriptional networks predating cognition-associated pyramidal lineages are restructured by erythropoietin

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By Manvendra Singh, Ying Zhao, Vinicius Daguano Gastaldi, Sonja M. Wojcik
| BioRxiv
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