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Sora Yoon

As seen in: BioRxiv, Cell Press, Academic Radiology
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Articles by Sora Yoon

Single-allele chromatin tracing reveals cytokine-dependent super-enhancer repositioning in CD4 + T cells

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By Atishay Jay, Yeqiao Zhou, Sora Yoon, Bereketab Abeje, Aditi Chandra, Michaël F. Michieletto, Julia Wald, Jorge Henao-Mejia, Arjun Raj, Robert B. Faryabi, Golnaz Vahedi
| Cell Press Verified
Keywords chromatin tracing microscopy paralogous transcription factors ETS1 FLI1 enhancers gene dosage T helper cells cytokines T cells Get full text access Log in, subscribe or purchase for full access. References 1. Vahedi, G. ∙ Kanno, Y. ∙ Sartorelli, V. ... Transcription factors and CD4 T cells seeking identity: masters, minions, setters and spikers Immunology. 2013; 139:294-298 2. Jay, A. ∙ Pondevida, C.M. ∙ Vahedi, G. The epigenetic landscape of fate decisions in T cells Nat. Immunol.
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Single-Allele Chromatin Tracing Reveals Genomic Clustering of Paralogous Transcription Factors as a Mechanism for Developmental Robustness in T Cells

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By Atishay Jay, Yeqiao Zhou, Sora Yoon, Bereketab Abeje
| BioRxiv
Abstract In metazoans, gene duplication has given rise to paralogous transcription factors, which have functionally diversified to control cellular differentiation. While the majority of paralogous TFs are dispersed across different chromosomes, some remain clustered raising the question of whether genomic proximity confers any evolutionary advantage for TF clusters. To address this, we investigated a ~1 Mbp locus containing two ETS family paralogs, Ets1 and Fli1.
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Author Response to “Letter to the Editor: Beyond Scrubs: Unlocking the Essence of Physician Attire in Patient-Centric Radiology Practice”

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By Derek Nguyen, Sora Yoon, Jay Baker, Stamatia Destounis
| Academic Radiology Verified
We appreciate Dr Valeria Del Castillo and her co-authors’ interest in our research and manuscript (). Their suggestion to conduct a similar study within their patient population, considering unique cultural and socioeconomic contexts, would be an important step in understanding patient preferences further. The potential outcomes of such research could provide valuable insights into the worldwide impact of health care provider attire on patient perception after the pandemic.
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A multi-enhancer hub at the Ets1 locus controls T cell differentiation and allergic inflammation through 3D genome topology

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By Aditi Chandra, Michaël F. Michieletto, Naomi Goldman, Sora Yoon
| BioRxiv
New Results doi: https://doi.org/10.1101/2022.10.28.514213 Abstract Multi-enhancer hubs are spatial clusters of enhancers which have been recently characterized across numerous developmental programs. Yet, the functional relevance of these three-dimensional (3D) structures is poorly understood.
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