Souhail Djebari
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Posterior parietal cortex oscillatory activity reflects persistent spatial memory impairments induced by early hippocampal amyloidosis in male mice
Introduction The posterior parietal cortex (PPC) is an associative cortical area situated in the posterior segment of the parietal lobe. It functions as a hub for processing sensory inputs, particularly from somatic and visual regions, synthesising this information to construct a representation of the body's position in space (Buneo & Andersen, 2006; Jacobs et al., 2012).
Low dose of a non-urea selective GIRK channel activator improves hippocampal-dependent synaptic plasticity and memory disrupted by amyloid-β oligomers
Abstract Increased neural activity characterizes early Alzheimers disease (AD), serving as a prognostic indicator for disease progression and cognitive decline. Mechanisms that drive this hyperactivity and their behavioral effects remain mostly unrevealed, although normalizing altered excitability levels has been shown to reverse cognitive impairment in early AD, both in animals and humans.
La plasticidad sináptica nos permite aprender a montar en bici y recordar momentos emocionantes
¿Alguna vez se ha preguntado qué sucede en nuestro cerebro cuando aprendemos a montar en bici? ¿Por qué una vez aprendemos a ejecutar los movimientos y a mantener el equilibrio lo recordamos de por vida? ¿Y cómo nos acordamos con todo lujo de detalles de momentos especiales de nuestra vida? La respuesta a de qué manera aprendemos y recordamos cosas radica en un fascinante fenómeno conocido como plasticidad sináptica.
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