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Melissa Ford on Muck Rack

Melissa Ford

Verified
As seen in: BlogHer, Nature, Edutopia, GeekDad, Tri-County Times, The Dallas Express, The Nome Nugget, The Mercury Bay Informer
Blogging & Social Media Editor at BlogHer (blogher.com) and author (melissafordauthor.com)
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Articles

Structural basis for selective and potent degradation of IRAK4 by KT-474

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By Xue Fei, Anand Ramanathan, Melissa Ford Verified, Veronica Campbell, Xiaozhang Zheng, Haoran Li, Hari Kamadurai, Richard Miller, Xin Huang, Matthew Weiss, Nello Mainolfi, Xiao Zhu, Caroline A. Daigle, Mike Sintchak, Steven Kazmirski
| Nature Verified
Abstract Targeted protein degradation has emerged as a promising drug modality, with potential applications across many immuno-inflammatory diseases. KT-474 is an orally bioavailable interleukin-1 receptor-associated kinase 4 (IRAK4) heterobifunctional degrader evaluated in clinical trials for atopic dermatitis and hidradenitis suppurativa. Here we present structural, biophysical, and computational characterization of an IRAK4:KT-474:CRBN/DDB1 complex.
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Childhood Books

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By Melissa Ford Verified
| stirrup-queens.com
It started with the Westing Game. The e-book went on sale, and while we own multiple copies of the paper version, we decided we needed a copy to keep in our pocket — a boost for a bad day. Then it was Beverly Cleary’s books. How could we walk through the world without the ability to read about Ramona whenever the mood arose? We may be regressing.
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#Microblog Monday 441: Kindergarten

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By Melissa Ford Verified
| stirrup-queens.com
Not sure what #MicroblogMondays is? Read the inaugural post which explains the idea and how you can participate too. ******* The twins’ Kindergarten teacher was an incredible educator. I stayed in touch with her after the kids moved through other grades and the teacher moved out of the area. The twins invited her to their B’nai Mitzvah because they loved her so much. I reached out to give her an update about the twins, and she shared that she was now a grandmother and sent along pictures.
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