Matthew Weiss on Muck Rack

Matthew Weiss

Raleigh
As seen in: Nature, Wiley Online Library, BMJ Open, ACS Publications, JAMA (The Journal of the American Medical Association), Yahoo, KTLA-TV (Los Angeles, CA), Los Angeles Magazine, KOIN-TV (Portland, OR), WOOD-TV (Grand Rapids, MI) and
Sommelier,Co-Host of @NCFBPod, Wine Rep @TheWinebowGroup , NY Sports Extremist, Self Proclaimed Dog Whisperer.
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Articles

Structural basis for selective and potent degradation of IRAK4 by KT-474

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By Xue Fei, Anand Ramanathan, Melissa Ford Verified, Veronica Campbell, Xiaozhang Zheng, Haoran Li, Hari Kamadurai, Richard Miller, Xin Huang, Matthew Weiss, Nello Mainolfi, Xiao Zhu, Caroline A. Daigle, Mike Sintchak, Steven Kazmirski
| Nature Verified
Abstract Targeted protein degradation has emerged as a promising drug modality, with potential applications across many immuno-inflammatory diseases. KT-474 is an orally bioavailable interleukin-1 receptor-associated kinase 4 (IRAK4) heterobifunctional degrader evaluated in clinical trials for atopic dermatitis and hidradenitis suppurativa. Here we present structural, biophysical, and computational characterization of an IRAK4:KT-474:CRBN/DDB1 complex.
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Mo1918 NEOADJUVANT CHEMORADIOTHERAPY IS ASSOCIATED WITH REDUCED POSTOPERATIVE PANCREATIC FISTULA FOLLOWING PANCREATODUODENECTOMY

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By Julien Hohenleitner, Daniel King, Elliot Newman, Abdullah Khalid, Daniel King, Sepideh Gholami, Danielle K. DePeralta, Matthew Weiss, Murtuza Hassan, Elliot Newman, Marcovalerio Melis
| Gastrointestinal Endoscopy Verified
Also available on ScienceDirect
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Important Dates and Ceremony Information for the 2026 Astra TV Awards

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By Matthew Weiss
| EIN Presswire
The Hollywood Creative Alliance has revealed their timeline for the 2026 Astra TV Awards taking place on Saturday, June 13, 2026 in Los Angeles. LOS ANGELES, CA, UNITED STATES, April 6, 2026 / EINPresswire.com/ -- The Hollywood Creative Alliance has officially opened submissions for the 2026 Astra TV Awards. The ceremony will take place on Saturday, June 13, 2026, in Los Angeles, with the venue to be announced alongside the nominations on May 27, 2026.
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