Stuart Benjamin Fass on Muck Rack

Stuart Benjamin Fass

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Articles

Single-cell multiregion epigenomic rewiring in Alzheimer’s disease progression and cognitive resilience

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By Zunpeng Liu, Shanshan Zhang, Benjamin James, Kyriaki Galani, Riley J. Mangan, Stuart Benjamin Fass, Chuqian Liang, Manoj M. Wagle, Carles Boix, Yosuke Tanigawa, Sukwon Yun, Yena Sung, Xushen Xiong, Na Sun, Lei Hou, Martin Wohlwend, Mufan Qiu, Xikun Han, Lei Xiong, Efthalia Preka, Lei Huang, William Li Verified, Li-Lun Ho, Amy Grayson, Julio C. Mantero, Alexey Kozlenkov, Hansruedi Mathys, Tianlong Chen, Stella Dracheva, David Bennett, Li-Huei Tsai, Manolis Kellis
| Cell Press Verified
Keywords Alzheimer's disease cognitive resilience single-cell multiomics epigenomics epigenomic stability epigenomic erosion epigenomic information microglial activation exhaustion regulatory network Introduction Alzheimer’s disease (AD) is the most common cause of dementia, characterized by progressive cognitive decline and neurodegeneration.1,2,3 A hallmark of AD is the accumulation of amyloid plaques and tau neurofibrillary tangles (NFTs), which disrupt synaptic integrity and drive...
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