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Su Lui

As seen in: Nature, Wiley Online Library, Frontiers, Neurology, Psiquiatria.com
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Articles by Su Lui

Hippocampal subregion volume alterations at baseline and following antidepressant treatment in youth at high risk for bipolar disorder

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By Biqiu Tang, L. Rodrigo Patino, Thomas J. Blom, Jeffrey A. Welge, Jeffrey Strawn, Kaitlyn Bruns, Wenjing Zhang, Su Lui, Manpreet Singh, Melissa P. DelBello
| Nature Verified
Understanding hippocampal neurostructural alterations at baseline and following antidepressant treatment in high-risk youth, particularly within distinct subregions, is critical for elucidating bipolar disorder (BD) pathophysiology and treatment planning. In this prospective randomized clinical trial, 105 high-risk youth with a first-degree BD-I relative(s) and moderate to severe depression and/or anxiety disorder, along with 51 healthy controls (HCs), were recruited.
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Functional brain abnormalities of cognitive impairments in schizophrenia indicating higher integration of working memory than other domains - Molecular Psychiatry

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By Xing Li, Jiaxin Zeng, Naici Liu, Biqiu Tang, Hui Sun, Changjian Qiu, James Gold, Su Lui, Wenjing Zhang
| Nature Verified
Abstract Brain functional alterations associated with overall cognitive impairments and specific cognitive domains defined by MATRICS Consensus Cognitive Battery (MCCB) and the similarities among them remain unclear in schizophrenia. Comprehensive literature review and meta-analyses of cognitive task fMRI studies were conducted to identify whole-brain differences between schizophrenia patients and healthy controls, and subgroup analyses were also conducted for each MCCB domain.
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Associations among structural brain alterations, respiratory symptoms and cognitive impairment in patients with chronic obstructive pulmonary disease-related subclinical cognitive vulnerability: a multimodal neuroimaging study

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By Chunrong Wang, Shiwei Lin, Kun Zhao, Yafeng Zhan, Yingwei Qiu, Kewen Peng, Xinyu Wang, Su Lui, Yong Liu, Shijun Qiu
| Frontiers
Abstract Background: Chronic obstructive pulmonary disease (COPD) is a systemic condition that often results in cognitive impairment. Nevertheless, the central nervous system correlates of COPD-related cognitive decline are not well-defined, representing a critical knowledge gap. The present study aimed to investigate the relationship among respiratory symptoms, structural brain changes, and cognitive impairment in patients with COPD who have subclinical cognitive vulnerability (COPD-SCV).
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Charting brain morphology in international healthy and neurological populations - Nature Neuroscience

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By Zhizheng Zhuo, Peng Gao, Qing Cai, Feiyan Chen, Feng Chen, Kun Chen, Dan Cheng, Zaixu Cui, Yuhui Du, Min Guo, Hongjian He, Chu-Chung Huang, Yao Li, Ching-Po Lin, Weiqi Liu, Yuqi Luo, Su Lui, Mengjie Rong, Wen Wang, Zheng Wang, Ying Choon Wu, Haiyan Wu, Rongjun Yu, Zhen Yuan, Jianguo Zhang, Renlong Zhang, Zhanjun Zhang, Zhiqiang Zhang, Jiajia Zhu, Xujun Duan, Xi-Nian Zuo
| Nature Verified
Abstract Quantifying individual deviations in brain morphology from normative references is useful for understanding neurodiversity and facilitating personalized management of brain health. Here we report Chinese brain normative references using morphological imaging scans of 24,061 healthy volunteers from 105 sites, revealing later peak ages of lifespan neurodevelopmental milestones (1.2–8.9 years) than European/North American populations.
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Regional cerebellar structural deficits distinguish psychostimulant‐free ADHD youth with and without familial risk for bipolar I disorder: a cross‐sectional morphometric analysis - Tang - Journal of Child Psychology and Psychiatry - Wiley Online Library

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By Wenjing Zhang, Su Lui, Biqiu Tang, L. Rodrigo Patino
| Wiley Online Library Verified
Introduction Bipolar I disorder (BD) typically emerges during late childhood and adolescence (Perlis et al., 2009), and often initially manifests with symptoms of attention-deficit/hyperactivity disorder (ADHD) (Axelson et al., 2015; Singh, DelBello, Kowatch, & Strakowski, 2006; Tillman & Geller, 2006).
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Rapid amyloid-β clearance and cognitive recovery through multivalent modulation of blood–brain barrier transport - Signal Transduction and Targeted Therapy

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By Junyang Chen, Su Lui, Kui Luo, Xiaohe Tian
| Nature Verified
Abstract The blood‒brain barrier (BBB) is a highly selective permeability barrier that safeguards the central nervous system (CNS) from potentially harmful substances while regulating the transport of essential molecules. Its dysfunction is increasingly recognized as a pivotal factor in the pathogenesis of Alzheimer’s disease (AD), contributing to the accumulation of amyloid-β (Aβ) plaques.
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Distinct effects of early-stage and late-stage socioeconomic factors on brain and behavioral traits - Nature Neuroscience

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By Qiang Xu, Su Lui, Yuan Ji, Jingliang Cheng, Long Zhang, Bing Zhang, Wenzhen Zhu, Xiaojun Xu, Wen Qin, Feng Liu, Jiayuan Xu, Jia-Hong Gao, Feng Chen, Junfang Xian, Meiyun Wang, Zhaoxiang Ye, Xiaochu Zhang, Xi-Nian Zuo, Kai Xu, Shijun Qiu, Chunshui Yu
| Nature Verified
Abstract Socioeconomic status (SES) is a time-varying multidimensional construct with ill-defined dimension-specific and age-specific effects on brain and behavior. We investigated these effects in 4,228 young adults. From 16 socioeconomic indicators, assessed for early (0–10 years) and late (>10 years) stages, we constructed family, provincial, family adverse and neighborhood adverse socioeconomic dimensions.
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Estudios sobre esquizofrenia en China

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By Wen Zhang, Su Lui
| Psiquiatria.com
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Improved patient identification by incorporating symptom severity in deep learning using neuroanatomic images in first episode schizophrenia - Neuropsychopharmacology

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By Wenjing Zhang, Hong Yin, Su Lui
| Nature Verified
Abstract Brain alterations associated with illness severity in schizophrenia remain poorly understood. Establishing linkages between imaging biomarkers and symptom expression may enhance mechanistic understanding of acute psychotic illness. Constructing models using MRI and clinical features together to maximize model validity may be particularly useful for these purposes.
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Functional brain controllability in Parkinson's disease and its association with motor outcomes after deep brain stimulation

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By Su Lui
| Frontiers
Huaxi MR Research Center (HMRRC), Functional and Molecular Imaging Key Laboratory of Sichuan Province, Department of Radiology, West China Hospital of Sichuan University, Guoxue Xiang, Chengdu, China Research Unit of Psychoradiology, Chinese Academy of Medical Sciences, Guoxue Xiang, Chengdu, China Department of Neurosurgery, West China Hospital of Sichuan University, Chengdu, China School of Computer Science and Engineering, University of Electronic Science and Technology of China, Chengdu,...
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Cross-ancestry genome-wide association studies of brain imaging phenotypes - Nature Genetics

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By Meiyun Wang, Wenzhen Zhu, Xiaojun Xu, Wen Qin, Feng Liu, Sijia Wang, Su Lui, Feng Chen, Junfang Xian, Jia-Hong Gao, Xiaochu Zhang, Xi-Nian Zuo, Zhaoxiang Ye, Jingliang Cheng, Mulin Jun Li, Chunshui Yu
| Nature Verified
Abstract Genome-wide association studies of brain imaging phenotypes are mainly performed in European populations, but other populations are severely under-represented. Here, we conducted Chinese-alone and cross-ancestry genome-wide association studies of 3,414 brain imaging phenotypes in 7,058 Chinese Han and 33,224 white British participants.
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Covariation of preadult environmental exposures, adult brain imaging phenotypes, and adult personality traits - Molecular Psychiatry

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By Feng Chen, Meiyun Wang, Xiaochu Zhang, Wen Qin, Feng Liu, Qiang Xu, Su Lui, Xi-Nian Zuo, Longjiang Zhang, Zhaoxiang Ye, Tobias Banaschewski, Gareth Barker, Sylvane Desrivières, Herta Flor, Penny Gowland, Andreas Heinz, Rüdiger Brühl, Jean-Luc Martinot, Eric Artiges, Dimitri Papadopoulos Orfanos, Sarah Hohmann, Juliane H. Fröhner, Michael N. Smolka, Henrik Walter, Robert Whelan, Wen Shen, Yanwei Miao, Chunshui Yu, IMAGEN Consortium, CHIMGEN Consortium
| Nature Verified
Abstract Exposure to preadult environmental exposures may have long-lasting effects on mental health by affecting the maturation of the brain and personality, two traits that interact throughout the developmental process. However, environment-brain-personality covariation patterns and their mediation relationships remain unclear.
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Teaching NeuroImage: Intracerebral Seroma Secondary to Arterial-Venous Malformation

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By Chun Ma, Jie Li, Su Lui
| Neurology Verified
REQUIREMENTS If you are uploading a letter concerning an article: You must have updated your disclosures within six months: http://submit.neurology.org Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.
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