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Insights on feline infectious peritonitis risk factors and sampling strategies from polymerase chain reaction analysis of feline coronavirus in large-scale nationwide submissions
Keywords: feline infectious peritonitis; feline coronavirus; risk factor; sample selection; RT-PCR Introduction Feline infectious peritonitis is a fatal and progressive illness caused by feline coronavirus (FCoV), affecting domestic and wild felids globally.3 Feline coronavirus manifests in 2 forms: the low-virulence feline enteric coronavirus (FECV) and the high-virulence FIP virus (FIPV).1 Feline infectious peritonitis can be exhibited in 2 forms: the “wet” form, characterized by fluid...
Theileria orientalis Ikeda in Cattle, Alabama, USA
1. Background Theileria orientalis is a hemoprotozoan parasite belonging to the phylum Apicomplexa [1]. The infection of cattle with this parasite can lead to various adverse effects, including anemia, weakness, reduced milk production, diminished weight gain, abortion, and occasionally, death [2,3,4,5,6]. Researchers have identified eleven genotypes of T. orientalis (Sivakumar et al., 2014), with the most frequently encountered genotypes being Buffeli, Chitose, and Ikeda [1,6,7,8]. While T.
Veterinary Sciences | Free Full-Text | Comparative Evaluation of GS-441524, Teriflunomide, Ruxolitinib, Molnupiravir, Ritonavir, and Nirmatrelvir for In Vitro Antiviral Activity against Feline Infectious Peritonitis Virus
4. Discussion The development of antiviral drugs targeting FCoV replication is of great importance, particularly in the absence of a safe and approved vaccine for FIPV infection. In the case of antiviral drug development, it is crucial to target viral enzymes, essential for replication, while minimizing adverse effects on uninfected cells.
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