Sudip Bastakoti

Serum sickness is rare; however, there is a significant hypersensitivity reaction to streptokinase used in different cardiac problems. Treatment often involves discontinuing the offending agent and administering corticosteroids. This case underscores the complexities of managing prosthetic valve thrombosis and highlights the importance of monitoring and addressing complications of thrombolytic therapy.

1 INTRODUCTION Brucellosis is an endemic zoonotic disease that affects wildlife. Its transmission to humans occurs through direct contact with infected animals or contaminated animal products.