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Suk-Ying Tsang on Muck Rack

Suk-Ying Tsang

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Liquid-liquid phase separation of ATXN2L enhances mRNA translation in hepatocellular carcinoma

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By Shenghong Wang, Peilan Guo, Wenqiang Ma, Honglin Huang, Qianqian Zhang, Slawomir Wolczynski, Nafis A Rahman, Jiali Liu, Xuguang Du, Fengchao Wang, Jie Gao, Xiangdong Li, Suk-Ying Tsang
| Cell Reports Verified
Keywords HCC ATXN2L mRNA translation LLPS ADAM9 SGs Research topic(s) CP: molecular biology Introduction Hepatocellular carcinoma (HCC), the third leading cause of cancer-related mortality worldwide, exhibits a dismal 5-year survival rate (<50%) due to frequent metastasis and recurrence.1 Although various therapeutic strategies have been developed and widely applied in recent years, their efficacy remains limited.2 Therefore, elucidating novel mechanisms underlying HCC initiation and...
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