Sumasri Kotha on Muck Rack

Sumasri Kotha

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Development and validation of the predictive aplastic score system (PASS): a simplified tool to diagnose acquired aplastic anemia in adults

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By Gabriel Aleixo, Jiayin Zheng, Jimmy Lee, Eleonore Kaphan, Wei-Ying Jen, Mia Djulbegovic, Jairo Matthews, Tapan M Kadia, Timothy Olson, Regis de Latour, Flore Sicre de Fontbrune, Taha Bat, Courtney DiNardo, Daria V. Babushok, HeeJin Cheon, Stephanie Soewito, Neha Kalakuntla, Sumasri Kotha, Alex Rupsee
| Nature Verified
Abstract Acquired aplastic anemia (AA) can present similarly to inherited bone marrow failure syndromes (IBMFS) but treatment differs. AA diagnosis relies on excluding IBMFS; however, genetic testing is not always available, may delay care or be inconclusive. We developed the Predictive Aplastic Score System (PASS), a clinical tool using readily available data to distinguish AA from IBMFS in adults. The training cohort included 212 adults (162 AA, 50 IBMFS).
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