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Articles by Sunil Mathur
Activating RARβ to overcome immunomodulatory drug resistance in t(4;14) human myeloma
Abstract The t(4;14) translocation is a high-risk cytogenetic abnormality in multiple myeloma (MM) that results in overexpression of fibroblast growth factor receptor 3 (FGFR3) and enhanced MM proliferation, leading to poor prognosis.
Statistical bioinformatics with R
Statistical Bioinformatics provides a balanced treatment of statistical theory in the context of bioinformatics applications. Designed for a one or two semester senior undergraduate or graduate bioinformatics course, the text takes a broad view of the subject – not just gene expression and sequence analysis, but a careful balance of statistical theory in the context of bioinformatics applications.
ZNFX1 uses two-component ubiquitin circuitry to quarantine viral RNA
ArticleVolume 86, Issue 6p1164-1181.e12Open access Affiliations & Notes 1MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK 2MRC University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow G61 1QH, UK Article Info Publication History: Received June 16, 2025; Revised October 9, 2025; Accepted February 19, 2026 DOI: 10.1016/j.molcel.2026.02.015 External LinkAlso available on ScienceDirect External Link...
Comparative Efficacy of Transurethral Laser Ablation Versus Conventional Methods in the Management of Recurrent Non-Muscle-Invasive Bladder Tumours
Specialty Please choose I'm not a medical professional. Allergy and Immunology Anatomy Anesthesiology Biostatistics Cardiac/Thoracic/Vascular Surgery Cardiology Critical Care Dentistry Dermatology Diabetes and Endocrinology Emergency Medicine Epidemiology and Public Health Family Medicine Forensic Medicine Gastroenterology General Practice Genetics Geriatrics Health Policy Hematology HIV/AIDS Hospital-based Medicine I'm not a medical professional.
Targeting erbB Pathways in breast cancer: Dual Kinase Inhibition for B
Peeyush N Goel,1,2,* Makoto Katsumata,3,* Wei Qian,4 Sunil Mathur,4 Mei Q Ji,1 Arabinda Samanta,1 Payal Grover,1 George Sgouros,5 Jenny C Chang,4 Mark I Greene1 1Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104-6082, USA; 2Children’s Hospital of Philadelphia, Philadelphia, PA, 19104-6082, USA; 3Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA; 4Dr. Mary and Ron...
Treatment at Twilight: An analysis of therapy patterns and outcomes in adults 80 years and older with advanced or metastatic non-small cell lung cancer
This paper is only available as a PDF. To read, Please Download here. Abstract The aim of this study is to assess treatment patterns, survival outcomes, and factors influencing systemic treatment decisions in adults ≥80 years with non-small cell lung cancer (NSCLC). This was a retrospective national cancer database (NCDB) study assessing outcomes in adults ≥80 years with advanced NSCLC.
Pleural empyema secondary to xanthogranulomatous pyelonephritis
Pleural empyema secondary to xanthogranulomatous pyelonephritis Adam Maxwell1, Alison Kent1, Marianne Tinkler1, Sunil Mathur2, Andy Beale3 1 Respiratory Department, Great Western Hospitals NHS Foundation Trust, Swindon, UK 2 Urology Department, Great Western Hospitals NHS Foundation Trust, Swindon, UK 3 Radiology Department, Great Western Hospitals NHS Foundation Trust, Swindon, UK Correspondence to Dr Adam Maxwell, Great Western Hospitals NHS Foundation Trust, Swindon SN3 6BB, UK;...
Pleural empyema secondary to xanthogranulomatous pyelonephritis
Pleural empyema secondary to xanthogranulomatous pyelonephritis Adam Maxwell1, Alison Kent1, Marianne Tinkler1, Sunil Mathur2, Andy Beale3 1Respiratory Department, Great Western Hospitals NHS Foundation Trust, Swindon, UK 2Urology Department, Great Western Hospitals NHS Foundation Trust, Swindon, UK 3Radiology Department, Great Western Hospitals NHS Foundation Trust, Swindon, UK Correspondence to Dr Adam Maxwell, Great Western Hospitals NHS Foundation Trust, Swindon SN3 6BB, UK;...
Photocrosslinking Activity-Based Probes for Ubiquitin RING E3 Ligases
Highlights • Photoactivated activity-based probes developed for large class of ubiquitin E3 ligases • ABPs are compatible with divergent RING E3 activation mechanisms • Parallelized E3 profiling and detection of growth factor-induced E3 activation Summary Activity-based protein profiling is an invaluable technique for studying enzyme biology and facilitating the development of therapeutics.
Digitalization of SMEs: What every small manufacturer should learn from the auto industry
Throughout industrial history, at the core of any thriving economy has been a flourishing manufacturing sector. Manufacturing industry in India has also gone through various phases of development over the period of time and promises to be one of the high growth sectors in the coming years.Innovative solutions in the fields of software and automation are increasingly finding acceptance among manufacturers, process industries and machine builders ( OEMs ).
Heralding manufacturing growth: SMEs in India need to move from automation to autonomy
The 'Make in India' initiative aims to boost the contribution of the manufacturing sector from 15% to 25% of the GDP , by 2022. When this growth happens, there will be two factors driving it. First, the local demand and then the capex driven by FDI. Roughly an additional trillion dollars of capex can potentially be added to the country's economy soon.
Predictors of Underrepresented Nursing Students' School Satisfaction, Success, and Future Education Intent
The United States is steadily becoming more diverse. According to the U.S. Census Bureau in 2012, minority groups comprised 37% of the population. Moreover, if current population trends continue, the minority population will be the majority by 2043 (U.S. Census Bureau, 2012). In contrast to the diversity of the U.S. population, the health care workforce remains predominantly White.
Make in India: Maximising manufacturing competence
Of late there has been a renewed buzz in Indian industry about manufacturing. The government of India has taken several initiatives for growth of the manufacturing sector in the country, the most notable being its 'Make in India' programme. Under 'Make in India,' the country is being projected as one of the most attractive destinations in the world to set up manufacturing.
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