Suramya Asthana on Muck Rack

Suramya Asthana

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Articles

Oxysterol accumulation in aging cells alters GPCR signalling

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By Suramya Asthana, Anant Verma, Arnab K Nath, Baivabi Bhattacharya
| biorxiv.org
Abstract Organismal aging is accompanied by the accumulation of senescent cells in the body, which drives tissue dysfunction. Senescent cells have a distinctive profile, including proliferation arrest, resistance to apoptosis, altered gene expression, and high inflammation. Despite global signalling and metabolic dysregulation during senescence, the underlying reasons for changes in signalling remain unclear.
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Modulated protein-sterol interactions drive oxysterol-induced impaired CXCR4 signalling

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By Deepak Saini, K. Ganapathy Ayappa, Anant Verma, Suramya Asthana
| biorxiv.org
Thank you for your interest in spreading the word about bioRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. Message Subject (Your Name) has forwarded a page to you from bioRxiv Message Body (Your Name) thought you would like to see this page from the bioRxiv website.
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