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Sydney Clarice Joseph

As seen in: BioRxiv
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Articles

Determining susceptibility loci in triple negative breast cancer using a novel pre-clinical model

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By Samson Simon, William Simmons, MinJeong Kim, Sydney Clarice Joseph
| BioRxiv
Abstract Breast cancer (BC) is the most common cancer and the second cause of death in US women. Our lack of understanding of how genetic variants affect molecular mechanisms that mediate BC aggression poses a substantial obstacle to advancements in cancer diagnosis and therapy. To examine genetic variants on BC traits, a novel murine model was created with robust phenotypic and genomic variation.
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FXR agonism with bile acid mimetic reduces pre-clinical triple-negative breast cancer burden

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By Samson Simon, MinJeong Kim, Sydney Clarice Joseph, Margaret Sue Bohm
| Preprints.org
Preprint Article Version 1 This version is not peer-reviewed Version 1 : Received: 25 January 2024 / Approved: 25 January 2024 / Online: 26 January 2024 (11:49:34 CET) Joseph, S.C.; Eugin Simon, S.; Bohm, M.S.; Kim, M.; Pye, M.E.; Simmons, B.W.; Graves, D.G.; Thomas-Gooch, S.M.; Tanveer, U.A.; Holt, J.R.; Ponnusamy, S.; Sipe, L.M.; Hayes, D.N.; Cook, K.L.; Narayanan, R.; Pierre, J.F.; Makowski, L. FXR agonism with bile acid mimetic reduces pre-clinical triple-negative breast cancer burden.
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