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Syndi Barish

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Articles

The molecular landscape of hypertrophic cardiomyopathy across disease stages and genotypes

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By Minwoo Kim, Zaofeng Yang, Liang Ma, Eleonora Adami, Yuri Kim, Sean L. Zheng, Corinna Losert, Henrike Maatz, Gabriela Venturini, Qi Shi, Meraj Neyazi, Martin Beyer, Eric Wei, Amanda Adam, Abhilash Suresh, Daniel Reichart, Eric Lindberg, Kemar Brown, David Saúl, Anna Gartner, Michael Lee, Nikolay Shvetsov, Syndi Barish, Natalia López Anguita, Viktoria Strohmenger
| Science Magazine Verified
Abstract Supplementary Materials REFERENCES AND NOTES Information & Authors Metrics & Citations Check Access References Figures Tables Media Share This article has 0 eLetter . Abstract Hypertrophic cardiomyopathy (HCM) is marked by asymmetric cardiac wall thickening, hypercontractility, diastolic dysfunction, and fibrosis. Pathogenic sarcomere gene variants cause HCM, but comparable abnormalities occur in patients with unexplained disease, albeit with fewer adverse events.
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