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Szintia Barnai

As seen in: Cell Press
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Articles

Store-independent activation of STIM1-ORAI1 by SPCA2 determines the basal CFTR activity in secretory epithelial cells

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By Aletta Kata Kiss, Arpad Varga, Marietta Görög, Tamara Madácsy, Petra Pallagi, Viktória Szabó, Petra Susánszki, Dániel Varga, Ingrid Hegnes Sendstad, Tim Crul, Boldizsár Jójárt, Bálint Tél, Zsófia Horváth, Anita Balázs, György Lázár, Miklós Erdélyi, Shmuel Muallem, Szintia Barnai, József Maléth, Peter Biro
| Cell Press Verified
Keywords epithelial ion secretion CFTR ORAI1 channel Ca2+ signaling store-independent Ca2+ influx 3D cultures human apical-out organoids STIM1 SPCA2 adenylyl cyclases Introduction Secretory epithelial cells are essential orchestrators of organ physiology by determining the composition and volume of bodily fluids via vectorial transport of ions and water.
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