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Taghreed Suliman on Muck Rack

Taghreed Suliman

As seen in: Nature, BioRxiv, eLife
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Articles

Extracellular vesicles from stem cells rescue cellular phenotypes and behavioral deficits in SHANK3-associated ASD neuronal and mouse models - Cell Death & Disease

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By Ashwani Choudhary, Idan Rosh, Yara Hussein, Shai Netser, Aviram Shemen, Taghreed Suliman, Wote Amelo Rike, Lilach Simchi, Boris Shklyar, Ahmad M. Abu-Akel, Assaf Zinger, Daniel Offen, Shlomo Wagner, Shani Stern
| Nature Verified
Abstract Extracellular vesicles (EVs) are lipid bilayer-enclosed structures that mediate intercellular communication by transferring diverse cargoes, including RNA and proteins. SHANK3, a synaptic scaffolding protein critical for synapse structure and function, is implicated in autism spectrum disorder (ASD) and Phelan-McDermid Syndrome (PMS). Early hyperexcitability in cortical neurons is a characterized endophenotype in ASD.
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DeePosit, an AI-based tool for detecting mouse urine and fecal depositions from thermal video clips of behavioral experiments

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By David Peles, Shai Netser, Natalie Ray, Taghreed Suliman
| eLife
eLife Assessment This manuscript presents an important machine-learning-based approach to the automated detection of urine and fecal deposits by rodents, key ethological behaviors that have traditionally been very poorly studied. The strength of evidence for the claim is solid, showing accuracy near 90% across several contexts. Training and testing for the specific contexts used by other experimenters, however, is probably warranted to make the model most relevant to the data that may be analyzed.
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DeePosit: an AI-based tool for detecting mouse urine and fecal depositions from thermal video clips of behavioral experiments

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By David Peles, Shai Netser, Natalie Ray, Taghreed Suliman
| BioRxiv
Abstract In many mammals, including rodents, social interactions are often accompanied by active urination (micturition), which is considered a mechanism for spatial scent marking. Urine and fecal deposits contain a variety of chemosensory signals that convey information about the individual's identity, genetic strain, social rank, and physiological or hormonal state.
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