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Tanner Bartholow on Muck Rack

Tanner Bartholow

As seen in: Nature, BioRxiv, Archives of Pathology
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Articles

Clinical and histopathological characterization of metastatic lobular breast cancer: lessons learned from post-mortem tissue donation programs - npj Breast Cancer

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By Gitte Zels, Karen Van Baelen, Alexander Chang, Anirudh Pabba, Maxim De Schepper, Marion Maetens, François Richard, Josephine Van Cauwenberge, Tatjana Geukens, Kristien Borremans, Amena Mahdami, HA NGUYEN, Hà Nguyễn, ha nguyễn, Sophia Leduc, Patrick Neven, Hans Wildiers, Vincent Vandecaveye, Raphaëla Dresen, Rohit Bhargava, Tanner Bartholow, Neil M. Carleton, Ye Cao, Jie Bin Liu, Abdalla Wedn, Hunter Waltermire, Morgan Cody, Lori C. Miller, Margaret Rosenzweig, Julia Foldi, Marija Balic, Christoper Deible, Christine Hodgdon, Stephanie Walker, Adrian Lee, Steffi Oesterreich, Giuseppe Floris, Christine Desmedt, Wouter Van Den Bogaert
| Nature Verified
Abstract While primary invasive lobular carcinoma (ILC) is well characterized, metastatic ILC remains understudied. Within the post-mortem tissue donation programs, UPTIDER (Belgium) and Hope for Others (USA), we first aimed to explore intra-patient heterogeneity of key prognostic and predictive markers (stromal tumor-infiltrating lymphocytes (sTIL), estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2) and KI67).
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Hope for Others: Research Results from the University of Pittsburgh Rapid Autopsy Program for Breast Cancer

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By Alexander Chang, Marija Balic, Rohit Bhargava, Tanner Bartholow
| BioRxiv
Abstract Breast cancer affects 1/8 of women throughout their lifetimes, with 90% of cancer deaths being caused by metastasis. However, metastasis poses unique challenges to research, as complex changes in the microenvironment in different metastatic sites and difficulty obtaining tissue for study hinder the ability to examine in depth the changes that occur during metastasis. Rapid autopsy programs thus fill a unique need in advancing metastasis research.
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