Skip To Main Content
Taochen He on Muck Rack

Taochen He

As seen in: Nature, Wiley Online Library
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile
Back to Taochen He’s profile

Articles by Taochen He

DDR1 sustains ferroptosis resistance in pancreatic ductal adenocarcinoma via SLC40A1-mediated iron homeostasis

|
By Luting Zhang, Sheng Xu, Xu-an Wang, Xinyi Zhang, Ganggang Wang, Mengmeng Liu, Yazhou Wang, Yifei Zhang, Taochen He, Kai Ding, Yu Chen, Xin Liang, Bing Y. Zhu, Wenquan Wang, Jingjing Li, Wenhui Lou, Liang Liu, Kai Xuan Cheong, Qianzhi Ni
| Nature Verified
Abstract Integrated single-cell transcriptomics and clinical analyses reveal elevated DDR1 expression in pancreatic ductal adenocarcinoma (PDAC) tissues, which correlates with poor prognosis. Mechanistically, collagen-activated Discoidin Domain Receptor 1 (DDR1) recruits SHC1 to activate the MAPK/ERK pathway, thereby driving transcriptional upregulation of SLC40A1 via the ERK-MYC axis.
Open in Who Shared Issue with article?

The Evolutionary Trajectory and Prognostic Value of GITR+ Tregs Reprogramed by Tumor‐Intrinsic PD‐1/c‐MET Signaling in Pancreatic Cancer

|
By Jiande Han, Hanlin Yin, Taochen He, Junyi He
| Wiley Online Library Verified
1 Introduction Pancreatic ductal adenocarcinoma (PDAC) is an exceptionally aggressive cancer with a low global incidence but remains one of the most lethal malignancies, exhibiting a five-year survival rate below 13% and increasing in prevalence in recent years.[1] Despite significant advancements in immunotherapy that have enhanced outcomes for various cancers, its efficacy in treating PDAC remains limited.[2, 3] The reasons for this are multifaceted, with one major factor being the highly...
Open in Who Shared Issue with article?

Poor clinical outcomes and immunoevasive contexture in CD161+CD8+ T cells barren human pancreatic cancer

|
By Qiangda Chen, Hanlin Yin, Zhenlai Jiang, Taochen He
| bmj.com
Clinical/translational cancer immunotherapy Poor clinical outcomes and immunoevasive contexture in CD161+CD8+ T cells barren human pancreatic cancer Statistics from Altmetric.com Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.
Open in Who Shared Issue with article?
Show More