Taylor Engdahl on Muck Rack

Taylor Engdahl

Nashville, Washington, D.C.
As seen in: Nature, American Society for Microbiology (ASM), VUMC Reporter
Covers:  infectious diseases, vaccines, COVID-19, pandemics, grad school
Scientific advisor @DARPA. Passionate about all things pandemic preparedness. @VUMC_Vaccines alum. She/her/hers. (views my own)

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Taylor Engdahl’s Biography

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Ph.D. candidate at Vanderbilt University

Taylor Engdahl’s Journalist Portfolio

SARS-CoV-2 is changing. What does that mean for vaccines and treatments?

SARS-CoV-2 is changing. What does that mean for vaccines and treatments?

Viruses exist in a constant arms race with the host's immune system. As the immune system fights off a virus,…

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The lonely marathon run that transformed my approach to graduate school

The lonely marathon run that transformed my approach to graduate school

In 2020, I had one big personal goal: to run my first marathon, a Rock n' Roll series race in Nashville, Tenn…

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Articles

Comparison of uridine and N1-methylpseudouridine mRNA platforms in development of an Andes virus vaccine - Nature Communications

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By Ivan Kuzmin, Perry T. Wasdin, Taylor Engdahl, Ivelin S. Georgiev, Robert Abbott
| Nature Verified
Abstract The rodent-borne Andes virus (ANDV) causes a severe disease in humans. We developed an ANDV mRNA vaccine based on the M segment of the viral genome, either with regular uridine (U-mRNA) or N1-methylpseudouridine (m1Ψ-mRNA). Female mice immunized by m1Ψ-mRNA developed slightly greater germinal center (GC) responses than U-mRNA-immunized mice.
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Computationally restoring the potency of a clinical antibody against Omicron - Nature

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By Thomas Desautels, Kathryn T Arrildt, Adam Zemla, Seth J. Zost, Elad Binshtein, Bernadeta Dadonaite, Taylor Engdahl, Laura S. Handal, Bradley Whitener, James Case, Larissa B. Thackray, Jesse Bloom, Michael Diamond Verified, Robert Carnahan
| Nature Verified
Abstract The COVID-19 pandemic underscored the promise of monoclonal antibody-based prophylactic and therapeutic drugs1,2,3 and revealed how quickly viral escape can curtail effective options4,5. When the SARS-CoV-2 Omicron variant emerged in 2021, many antibody drug products lost potency, including Evusheld and its constituent, cilgavimab4,5,6.
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Mechanistic basis for potent neutralization of Sin Nombre hantavirus by a human monoclonal antibody - Nature Microbiology

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By Robert Stass, Taylor Engdahl, Rachael M. Wolters, Laura S. Handal
| Nature Verified
Cell lines Expi293F cells (human, female origin) were cultured in suspension at 37 °C in 8% CO2 with shaking at 125 r.p.m. in Freestyle F17 Expression Medium (Gibco) supplemented with 10% Pluronic F-68 and 200 mM of l-glutamine. ExpiCHO cells (hamster, female origin) were cultured in suspension at 37 °C in 8% CO2 with shaking at 125 r.p.m. in ExpiCHO Expression Medium (Thermo Fisher).
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