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Robert Abbott on Muck Rack

Robert Abbott

As seen in: Nature, Memory Studies, PNAS, Cell Press, Cell Reports, Radiological Society of North America, Lead Stories
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Articles

Comparison of uridine and N1-methylpseudouridine mRNA platforms in development of an Andes virus vaccine - Nature Communications

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By Ivan Kuzmin, Perry T. Wasdin, Taylor Engdahl, Ivelin S. Georgiev, Robert Abbott
| Nature Verified
Abstract The rodent-borne Andes virus (ANDV) causes a severe disease in humans. We developed an ANDV mRNA vaccine based on the M segment of the viral genome, either with regular uridine (U-mRNA) or N1-methylpseudouridine (m1Ψ-mRNA). Female mice immunized by m1Ψ-mRNA developed slightly greater germinal center (GC) responses than U-mRNA-immunized mice.
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Fact Check: Republicans DID Thank Biden For Drone Strike That Killed Al Qaeda Leader Ayman Al-Zawahiri

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By Robert Abbott
| Lead Stories Verified
Did no Republicans thank U.S. President Joe Biden for taking out the leader of Al Qaeda? No, that's not true: Several GOP members of Congress publicly acknowledged Biden for the July 31, 2022 drone strike in Kabul, Afghanistan that killed Ayman al-Zawahiri, the leader of Al Qaeda and one of the conspirators behind 9/11. The claim was shared on a Twitter post (archived here) by Twitter user Dash Dobrofsky on August 1, 2022.
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By Jeong Hyun Lee, Catherine Nakao, Amber Le, Elise Landais, Oleksandr Kalyuzhniy, Xiaozhen Hu, Alessia Liguori, Robert Abbott, Michael Appel Verified
| Cell Reports Verified
Highlights • VRC01-class naive B cells can acquire many bnAb-like mutations after 1 immunization • VRC01-class Abs neutralizing multiple ΔN276 HIV pseudoviruses were elicited • Trimer-based but not minimal GT immunogen priming elicited key trimer-binding SHMs Summary Elicitation of HIV broadly neutralizing antibodies (bnAbs) is challenging because unmutated bnAb precursors are rare and seldom bind HIV envelope glycoprotein (Env) trimers.
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