Thomas E Gorochowski on Muck Rack

Thomas E Gorochowski

Bristol
As seen in: Nature, Science Magazine, JoVE- Journal of Visualized Experiments
Synthetic biologist, programmer of cells, and lover of all things visual. Wakes up in the morning to learn some of natures secrets and do a spot of fly fishing.
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Articles

From FAIR to CURE: guidelines for computational models of biological systems

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By Herbert Sauro, Eran Agmon, Michael L. Blinov, John Gennari, Joseph Hellerstein, Adel Heydarabadipour, Bartholomew Jardine, Elebeoba E. May, David Nickerson, Lucian P. Smith, Gary D. Bader, Frank Bergmann, Patrick Boyle, Andreas Dräger, James R Faeder, Song Feng, Juliana Bueno Freire, Fabian Fröhlich, James A. Glazier, Thomas E Gorochowski, Tomas Helikar, Henning Hermjakob, Stefan Hoops, Peter Hunter, Princess I Imoukhuede, Sarah Keating, Matthias König, Reinhard Laubenbacher, Leslie Loew, Carlos Lopez, Carlos López, William W. Lytton, Rahuman S. Malik-Sheriff, Andrew McCulloch, Pedro Mendes, Chris Myers Verified, Anna Niarakis, David van Niekerk, Brett G. Olivier, Ellen Quardokus, Nicole Radde, Johann M. Rohwer, Sven Sahle, James C. Schaff, Falk Schreiber, T. J. Sego, Janis Shin, Jacky L. Snoep, Rajanikanth Vadigepalli, H. Steven Wiley, Dagmar Waltemath, Ion I. Moraru, Lealem Mulugeta, Jerry G. Myers Jr, Alexander A. Patrie
| Nature Verified
Abstract Guidelines for managing scientific data have been established under the FAIR principles, requiring that data be Findable, Accessible, Interoperable, and Reusable. In many scientific disciplines, especially computational biology, both data and models are key to progress.
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Analysis and control of untemplated DNA polymerase activity for guided synthesis of kilobase-scale DNA sequences - Nature Communications

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By Adrian Woolfson, Gregory Linshiz, Blake T. Riley, Ifor Samuel, Loren Picco, Philipp Holliger, Lauren M. Oldfield, Andrew Hessel, Thomas E Gorochowski, Simeon. D. Castle, Thea C. T. Irvine
| Nature Verified
Abstract DNA polymerases are complex molecular machines capable of replicating genetic material using a template-driven process. While the copying function of these enzymes is well established, their ability to perform untemplated DNA synthesis is less well characterized. Here, we explore the ability of DNA polymerases to synthesize DNA fragments in the absence of a template.
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Data-driven inference of digital twins for high-throughput phenotyping of motile and light-responsive microorganisms

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By Andrea Giusti, Davide Salzano, Mario di Bernardo, Thomas E Gorochowski
| biorxiv.org
Abstract Light can affect the movement of microorganisms. These responses can drive collective behaviours like photoaccumulation and photodispersion, which play a key role in broader biological functions like photosynthesis. Our understanding of these emergent phenomena is severely limited by difficulties in obtaining data needed to establish accurate models that can serve as a basis for multi-scale analyses.
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