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Thomas LaBar

As seen in: PLOS Biology, BioRxiv, Cell Press
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Articles

A dynamic network model predicts the phenotypes of multicellular clusters from cellular properties

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By Piyush Nanda, Julien Barrere, Thomas LaBar, Andrew Murray
| Cell Press Verified
Grosberg R.K. Strathmann R.R. The evolution of multicellularity: a minor major transition?. Annu. Rev. Ecol. Evol. Syst. 2007; 38: 621-654 A twelve-step program for evolving multicellularity and a division of labor. Bioessays. 2005; 27: 299-310 Tong K. Bozdag G.O. Ratcliff W.C. Selective drivers of simple multicellularity. Curr. Opin. Microbiol. 2022; 67102141 Emergence of multicellularity in a model of cell growth, death and aggregation under size-dependent selection. J. R. Soc. Interface.
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Multicellular growth as a dynamic network of cells

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By Piyush Nanda, Julien Barrere, Thomas LaBar, Andrew Murray
| BioRxiv
Abstract Cell division without cell separation produces multicellular clusters in budding yeast. Two fundamental characteristics of these clusters are their size (the number of cells per cluster) and cellular composition: the fractions of cells with different phenotypes. However, we do not understand how different cellular features quantitatively influence these two phenotypes.
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Evolutionary Repair Experiments as a Window to the Molecular Diversity of Life

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By Thomas LaBar, Yu-Ying Phoebe Hsieh, Andrew Murray Verified, Marco Fumasoni
| Cell Press Verified
Sandell L. Otto S.P. Probing the depths of biological diversity during the second century of genetics. Genetics. 2016; 204: 395-400 Cross F.R. Buchler N.E. Skotheim J.M. Evolution of networks and sequences in eukaryotic cell cycle control. Philos. Trans. R. Soc. B. 2011; 366: 3532-3544 Balasubramanian M.K. Bi E. Glotzer M. Comparative analysis of cytokinesis in budding yeast, fission yeast and animal cells. Curr. Biol. 2004; 14: 806-818 Diepeveen E.T. Gehrmann T. Abeel T. Laan L.
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