Thomas Lund
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Articles by Thomas Lund
Long-term follow-up of the transplant-eligible cohort of the EMN12/HOVON-129 study for primary plasma cell leukemia patients
To the editor: Primary plasma cell leukemia (pPCL) is a rare and aggressive plasma cell disorder [1, 2]. Compared to multiple myeloma (MM), pPCL is characterized by a higher frequency of poor-risk features, such as high-risk cytogenetic abnormalities (HRCAs) and elevated LDH [1, 2]. Although MM treatment has improved, the survival of pPCL patients remains poor [1, 2].
Unearthing heterogeneity in readiness and resistance to sustainable change and carbon footprints in organisations
Abstract Organisations can drive the sustainability transition if employees and organisational culture are prepared to adopt sustainability-relevant changes. We present a multilevel framework that models the cognitive and emotional dimensions of readiness and resistance to sustainable changes in organisations. This framework is used to study change readiness for plant-based workplace lunches among 62 Danish organisations.
Assessment of Liver Stiffness and Steatosis in Patients with Intestinal Failure: A Cross-Sectional Study
ORIGINAL RESEARCH article Front. Nutr. Sec.
Manglende vandtryk i område i Hvidovre er genskabt
På grund af driftsforstyrrelser tirsdag morgen har et område i Hvidovre omkring Hvidovrevej 278 og Høvedstensvej oplevet manglende vandtryk tirsdag morgen. Vandtrykket er nu genskabt og vandet er tilbage i hanerne. Oplever man grumset eller farvet vand i hanen, er dette ikke farligt. Man skal blot lade vandet løbe lidt og evt. rense/skylle filtre i haner og cisterner. Læs mere om hvad der sker ved vandafbrydelser her: Hvad sker der ved vandafbrydelser? – HOFOR
Ustabilt vandtryk på grund af strømsvigt
Grundet et større strømsvigt København kan HOFORs vandkunder have oplevet et ustabilt vandtryk mandag formiddag på grund af manglende strøm til de pumper, der understøtter vandtrykket. Oplever man grumset eller farvet vand i hanen, er dette ikke farligt. Man skal blot lade vandet løbe lidt og evt. rense/skylle filtre i haner og cisterner. Læs mere om hvad der sker ved vandafbrydelser her: Hvad sker der ved vandafbrydelser? – HOFOR
08.05.25 -- FDA Addresses U.S. Health Crisis With Voucher Program
Webinar: How Compliance-Driven CDMOs Win Sponsor Contracts In today's sciences landscape, compliance is no longer just a requirement, it's a competitive advantage. This MasterControl webinar explores how evolving global regulatory frameworks are reshaping sponsor expectations and increasing CDMO risk. Learn how digitally mature manufacturers can embed compliance into daily operations, avoid costly disruptions, and gain strategic edge in client audits, contract renewals, and market access.
Amager og Vesterbro er uden varmt vand og varme onsdag morgen
HOFOR arbejder på højtryk for at få varmen tilbage og forventer, at det vil ske i løbet af onsdag formiddag.
05.20.25 -- From Preparation To Compliance: DSCSA Implementation Takes Big Steps In 2025
Key Requirements To Ensure Patient Safety In Viral Vaccine Production Gain insight into the issues and obstacles faced by pharmaceutical companies, the current regulatory framework surrounding viral vaccines, and how one company is preparing for the next outbreak.
Envelop Me
If there's a technical thing nearly every audiophile knows, it's that low frequencies (LF) aren't directional. We tend to treat LF as monothink sub/sat systems in stereo, "LFE" in home-theater. But if the conclusions of a study by Thomas Lund, a researcher at Genelec OY (footnote 1), imply what they seem to, then that conviction is quite wrong.
Prospective phase II trial of [68Ga]Ga-NOTA-AE105 uPAR-PET/MRI in patients with primary gliomas: Prognostic value and Implications for uPAR-targeted Radionuclide Therapy | EJNMMI Research | Full Text
We adhered to the STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) guidelines for reporting. In this prospective clinical trial, eligible patients were enrolled from the Department of Neurosurgery at Copenhagen University Hospital, Rigshospitalet, between March 2017 and June 2022.
09.19.24 -- FDA Issues Revised Guidance On Controlling Nitrosamine Impurities In Pharmaceuticals
Visit METTLER TOLEDO at Pack Expo! Stop by booth 2939 to see live music, educational seminars, and demonstrations of product inspection solutions! We’ll showcase many new solutions including two x-ray inspection systems accessible for all budgets, combination inspection systems, metal detection solutions and a vision system integrated with a thermal transfer printer. All systems will be connected to ProdX data management software which is designed to save time and money, and keep data safe. More.
Maximal respiratory pressure after COVID‐19 compared with reference material in healthy adults: A prospective cohort study (The SECURe study)
1 INTRODUCTION COVID-19 has globally infected more than 772 million people with more than 6.9 million deaths as of December 11, 2023 (WHO, 2023). Chest pain, dyspnea and fatigue are some of the symptoms seen to persist in post-COVID condition (Ballering et al., 2022; Crook et al., 2021).
For the Love of Music: Loudness Normalization
From the early days of sound recording, compressors, limiters, and de-essers have been used to keep up the level, making most of the dynamic range of tape recorders and cutting machines. In listening tests, loudness is a typical confounder because it only takes a fraction of a decibel’s difference to systematically bias results in favor of louder examples. At normal listening levels, everybody likes louder, so what is the problem?
08.21.24 -- You Want Success With CDMOs? Think In Threes
Webinar: Advances in Oral GLP-1 Analogs for Obesity: Market Insights, Challenges, and Delivery Strategies Join us on September 12, 2024, at 11:00am EDT as we explore the impact of oral GLP-1 analogs on obesity treatment. We’ll cover their role in improving patient adherence and market expansion while addressing challenges like stability and bioavailability. Key topics include the significance of GLP-1 analogs, market growth, and innovative delivery strategies. Click here to learn more.
How Is Human Socioeconomic Position Linked With Dog Ownership Practices? A Study From Denmark
ABSTRACT Connections between dog ownership and socioeconomic position (SEP) are not well understood. This study examined associations between family and neighborhood levels of SEP and dog ownership, dog acquisition factors (purchase price and breed characteristics), and the purposes of owning a dog based on data from a survey carried out in Denmark in 2021. Participants (aged 18–89 years) were recruited using probability sampling (n = 2,112).
08.09.24 -- The Real Cost Of Poor Quality — And What You Should Do About It
The Critical Role Of Residue Removal In Cleanroom Biosafety Cabinets Learn about the significance of residue removal, how it is effectively performed in cleanrooms to ensure the compliance of biosafety cabinets, and the impact of proper residue removal. Spray Drying To Enable New Inhaled Drug Products The formulation and spray drying process can help manufacture a stable, highly respirable powder and deliver products that require a high drug load, a biologic, or rapid onset therapeutic.
In multiple myeloma, monthly treatment with zoledronic acid beyond two years offers sustained protection against progressive bone disease - Blood Cancer Journal
Dear Editor, Lytic bone destruction is one of the most devastating complications in Multiple Myeloma (MM). At diagnosis, more than half of patients have bone pain, and 90 percent of all patients with MM will experience bone destruction that may cause pain, pathological fractures, nerve root compression, hypercalcemia and potentially spinal cord compression [1].
04.10.24 -- From Ally To Adversary: BIO's Swift Rebuke Of WuXi
Latest Advances In Applied Nanotechnology For Formulating Better Amorphous Solid Dispersions and Monoclonal Antibodies Join us on May 1st to learn the latest in nanotechnology. Recent developments in leading nanotechnologies are enabling new formulation possibilities for more products, providing a better patient experience and stronger differentiation for biopharma innovators.
Pulmonary diffusing capacity for carbon monoxide and nitric oxide after COVID‐19: A prospective cohort study (the SECURe study)
1 INTRODUCTION After the initial surge of the coronavirus disease 2019 (COVID-19) pandemic, it became evident that the pulmonary effects of the disease often lasted far beyond the immediate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (Crook et al., 2021).
Cat and dog owners’ expectations and attitudes towards advanced veterinary care (AVC) in the UK, Austria and Denmark
Loading metrics Open Access Peer-reviewed Research Article Citation: Corr SA, Lund TB, Sandøe P, Springer S (2024) Cat and dog owners’ expectations and attitudes towards advanced veterinary care (AVC) in the UK, Austria and Denmark. PLoS ONE 19(3): e0299315. https://doi.org/10.1371/journal.pone.0299315 Editor: Francesca Baratta, University of Turin, ITALY Received: September 9, 2023; Accepted: February 8, 2024; Published: March 20, 2024 Copyright: © 2024 Corr et al.
Turbulence Transitions in Kelvin-Helmholtz Instability “Tube” and “Knot” Dynamics: Vorticity, Helicity, and Twist Waves
1. Introduction Evidence of vorticity dynamics driving accelerated and apparently more energetic transitions to turbulence in stratified shear flows has spanned almost four decades. Initial evidence was obtained from laboratory stratified shear flow studies of Kelvin–Helmholtz instabilities (KHIs) by Thorpe [1,2], who recognized their significance and coined the “Tube” and “Knot” (T&K) labels.
Treatment of primary plasma cell leukaemia with carfilzomib and lenalidomide-based therapy (EMN12/HOVON-129): final analysis of a non-randomised, multicentre, phase 2 study
Research in context Evidence before this study Primary plasma cell leukaemia is a rare and aggressive plasma cell dyscrasia with a dismal prognosis. We searched PubMed for published clinical trials from database inception until May 1, 2023, using the search terms “primary plasma cell leukaemia” OR “plasma cell leukaemia”. The search was restricted to clinical trials without any language restrictions.
Effect of once-per-day tacrolimus versus twice-per-day ciclosporin on 3-year incidence of chronic lung allograft dysfunction after lung transplantation in Scandinavia (ScanCLAD): a multicentre randomised controlled trial
Summary Evidence is low regarding the choice of calcineurin inhibitor for immunosuppression after lung transplantation. We aimed to compare the use of tacrolimus once per day with ciclosporin twice per day according to the current definition of chronic lung allograft dysfunction (CLAD) after lung transplantation.
Accelerating Atmospheric Gravity Wave Simulations Using Machine Learning: Kelvin‐Helmholtz Instability and Mountain Wave Sources Driving Gravity Wave Breaking and Secondary Gravity Wave Generation
1 Introduction Gravity waves (GWs) play prominent roles throughout Earth's atmosphere. They are generated at lower altitudes by various primary sources including airflow over topography (i.e., mountain waves, MWs), convection, and jet streams (Fritts & Alexander, 2003). Accounting for smaller-scale GW transports and influences remains a challenging problem due to the complex physics involved and the need for high-resolution simulations to describe detailed responses where these are important.
DeepDixon synthetic CT for [18F]FET PET/MRI attenuation correction of post-surgery glioma patients with metal implants
Claes N. Ladefoged1*, Flemming L. Andersen1, Thomas L. Andersen1, Lasse Anderberg1, Christian Engkebølle1, Karine Madsen1, Liselotte Højgaard1, Otto Henriksen1 and Ian Law1 1Department of Clinical Physiology and Nuclear Medicine, Rigshospitalet, University of Copenhagen, Denmark The final, formatted version of the article will be published soon.
A toxin-based approach to neuropeptide and peptide hormone discovery
1. Introduction Neuropeptides and peptide hormones (collectively referred to as signaling peptides) are important signaling molecules found throughout the Animal Kingdom (Jékely, 2013; Nikitin, 2015; Koch and Grimmelikhuijzen, 2019), controlling and regulating many diverse biological functions, ranging from metabolism and hunger to learning, pain, and mating (Russo, 2017).
Animals | Free Full-Text | Compete or Cooperate with ‘Dr. Google’? Small Animal Veterinarians’ Attitudes towards Clients’ Use of Internet Resources-A Comparative Study across Austria, Denmark and the UK
Open AccessArticle by Svenja Springer 1,2,*, Herwig Grimm 1, Peter Sandøe 2,3, Thomas Bøker Lund 2, Annemarie T. Kristensen 4 and Sandra A.
Kødspisere uden kvababbelser
Kronik. Det er helt i overensstemmelse med deres værdier, når danskerne fylder kød på tallerkenen. Et flertal synes, det er i orden at slå dyr ihjel for at spise dem, og 20 procent mener ikke, at dyr har krav på etiske hensyn. Peter sandøe Professor, Københavns Universitet Thomas Bøker Lund Lektor, Københavns Universitet
The Sponsors Perspective: Monitoring Immersive Audio - The Broadcast Bridge - Connecting IT to Broadcast
Genelec Senior Technologist Thomas Lund starts down the road to ideal monitoring for immersive audio by looking at what is real, and how that could or should be translated for the listener. Natural listening is immersive. Whether in a room or outdoors, sound is all around us.
Prospective study of physical and psychosocial risk factors for sickness absence
Aim To investigate the associations between psychosocial and physical work environment exposures and sickness absence from work taking into account health, health behaviour and employer characteristics known to affect sickness absence. Methods In 1995, a random sample of 5574 employees aged 18–64 years were interviewed. In 2000, 3792 of those still employed supplied data on days absent from work the year preceding the date of follow-up.
Digging deeper: How do different types of organic consumers influence the increasing organic market share?
Abstract Purpose This article aims to investigate how sub-markets with different degrees of maturity develop during a period of general organic growth, and how different consumer segments behave on these sub-markets. Design/methodology/approach This paper uses actual purchasing behaviour of six consumer segments with different attitudes towards food in general, and organic production and products in particular.
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