Tiankai Yin
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Overexpression of the signaling-coordinator GAB2 can play an important role in Acute Myeloid Leukemia progression
ResearchGeneticsOncology Open Access | 10.1172/JCI195929 J Clin Invest. https://doi.org/10.1172/JCI195929. Copyright © 2025, Kramer et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. View PDF Abstract Mutations that initiate AML can cause clonal expansion without transformation (“clonal hematopoiesis”).
Rapid and accurate remethylation of DNA in Dnmt3a-deficient hematopoietic cells with restoration of DNMT3A activity
Research Article CANCER Yang Li https://orcid.org/0000-0001-5182-5609, Haley J. Abel https://orcid.org/0000-0003-3110-8041, [...] , Michelle Cai https://orcid.org/0009-0001-4319-4509, Taylor A. LaValle https://orcid.org/0009-0000-6085-7186, [...] , Tiankai Yin https://orcid.org/0000-0003-0584-8791, Nichole M. Helton https://orcid.org/0000-0001-8308-9407, Amanda M. Smith https://orcid.org/0000-0002-8716-6745, Christopher A. Miller https://orcid.org/0000-0003-4266-6700, and Timothy J.
Acute Glycogen Synthase Kinase-3 Inhibition Modulates Human Cardiac Conduction:
JACC Journals › JACC: BTS › Archives › Vol. 7 No. 10 Highlights • Human cardiac slices cultured with SB216763 showed reduced conduction velocity and decreased excitability, as measured by dVm/dtmax, at 3 and 24 hours compared to slices cultured in control media. • Both overall and nuclear β-catenin levels increased, whereas NaV1.5 decreased, in human cardiac slices cultured with SB216763.
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