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Till Bärnighausen

As seen in: Arthritis & Rheumatology, Nature, Wiley Online Library, PLOS, PLOS Medicine, Journal of Epidemiology and Community Health, MDPI, The BMJ, The Conversation, Biomed Central (BMC) and
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Articles

Multimodal phenotypic classification of generalized anxiety and panic using structural MRI data and psychosocial factors: machine learning results from the German National Cohort (NAKO) study

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By Julian Gutzeit, Martin Weiß, Fabian Streit, Christiane Jockwitz, Berit Brandes, Marvin Wright, Christoph Friedrich, Margarethe Woeckel, Rafael T. Mikolajczyk, Thomas Keil, Stefanie Castell, Christopher L. Schlett, Till Bärnighausen, Fabian Bamberg, Matthias Günther, Tobias Pischon, Thoralf Niendorf, Michael F. Leitzmann, Patricia Bohmann, Kerstin Wirkner, Lilian Krist, Yanding Wang, Klaus Berger, Sebastian Walther, Hans J. Grabe, Jürgen Deckert, Svenja Caspers, Grit Hein, Tierney Kuhn, Johanna Klinger-König, Philine Betker, Jochen G. Hirsch, Angelika Erhardt-Lehmann
| Nature Verified
Abstract Anxiety disorders are common and impairing mental health conditions. Using data from 26,378 adults in the German National Cohort Study (NAKO), we investigated psychosocial and neuroimaging predictors of generalized anxiety disorder (GAD) symptoms and panic attacks. We conducted machine-learning analyses of 246 regions of interest from whole-brain imaging data in combination with psychosocial variables.
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PRIMARY-AI: outcomes-based standards to safeguard primary care in the AI era - Nature Medicine

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By Dian Zeng, Lorainne Tudor Car, Kamlesh Khunti, Yuanli Liu, Till Bärnighausen, Niels H. Chavannes, Pearse A. Keane, Holger Kunz, Lan Xue, Yih Chung Tham, Lorenzo Righetto Verified, Donald J. Boudreau, Qionghai Dai, Weiping Jia, Yang Liu Verified, Dinggang Shen, Jia Liu, Weixing Shen, John S. Ji, Zhong Lin Wang, Zhiyi Wang, Haibo Wang, Shenglan Tang, Chenyang Pei, Zehua Jiang, Zihao Zou, Yiming Qin, Huating Li, Yasha Wang, Dinesh Visva Gunasekeran, Sabrina Wong, Dong Xu, Ryan J. Urbanowicz, Liliana Laranjo, Ana Neves, Nan Liu, Neil M. Bressler, Rifat Atun, David C. Klonoff, Nigam H. Shah, Josip Car, Rupa Sarker, Phuoc Van Le
| Nature Verified
Artificial intelligence (AI) is being deployed at scale in primary care — from diagnostic support and risk stratification to triage and clinical documentation — without any agreed-upon outcomes-based framework for determining whether it strengthens or undermines continuity, coordination, comprehensiveness and people-centered care1. This is dangerous for the billions of people whose first contact with health systems is primary care.
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Intervention research to protect human health in the era of climate extremes

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By Till Bärnighausen, Helen Lumbard
| PLOS Medicine Verified
Loading metrics Citation: Bärnighausen T, Lumbard H (2026) Intervention research to protect human health in the era of climate extremes. PLoS Med 23(1): e1004918. https://doi.org/10.1371/journal.pmed.1004918 Published: January 29, 2026 Copyright: © 2026 Bärnighausen, Lumbard.
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