Timon D. Utecht on Muck Rack

Timon D. Utecht

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Articles

Tolerance to ferroptosis facilitates lipid metabolism and pathogenic type 2 immunity in allergic airway inflammation

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By Chantal Wientjens, Maria Doverman, Jelena Zurkovic, Tushar R. More, Jayagopi Surendar, Svetozar Nesic, Carola Sarici, Timon D. Utecht, Johanna Pohl, Jonathan Pollock, David Voehringer, Karsten Hiller, Christoph Thiele, Christoph Wilhelm
| Cell Press Verified
Keywords innate lymphoid cells ILC2 cysteine ferroptosis lipid metabolism fatty acids thioredoxin GPX4 asthma ROS Introduction Substantial progress has been made in understanding how metabolism modulates immune cell function, and cellular metabolism is emerging as an essential regulator of immune function.1 However, a fundamental gap remains in understanding the tissue-specific metabolic adaptations of immune cells in homeostasis and inflammation.
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