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Articles by Tina Su
Intracranial delivery of B7-H3-targeting CAR-T cells for recurrent glioblastoma: a phase 1 trial
Abstract Recurrent glioblastoma (rGBM) is a leading brain malignancy with few therapeutic options. Here we present the complete results of a phase 1 trial investigating the safety and efficacy of autologous B7-H3-targeting chimeric antigen receptor T (CAR-T) cell (TX103) therapy for the treatment of rGBM.
The liver-secreted protein FGL1 restrains a subset of innate-like B cell responses via the receptor TACI
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Keywords FGL1 TACI BAFF APRIL LAG-3 BCMA B cell inhibitory autoimmunity lupus Get full text access Log in, subscribe or purchase for full access. References 1. Zhu, Y. ∙ Yao, S. ∙ Chen, L. Cell surface signaling molecules in the control of immune responses: a tide model Immunity. 2011; 34:466-478 2. Chen, L. ∙ Flies, D.B. Molecular mechanisms of T cell co-stimulation and co-inhibition Nat. Rev. Immunol. 2013; 13:227-242 3.
By Tina Su, Jianwei He, Yuge Wang, Jiaoyan Huang, Baozhu Huang, Ala F. Nassar, Laure Willen, Mahya Eslami, ChunXiang Wu, Meiyi Huang, Jianping Zhang, Runxia Gu, Lan Ji, Ti Badri, Xuan Yang, Hyeon Jun Shin, Min-Jong Kang, Lokesh Sharma, Matthew Vesely, Yong Xiong Verified, Hongyu Zhao, Pascal Schneider, Jun Wang, Lieping Chen
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Cell Press
Verified
The Simplest Productivity System
By Tina Su Published in happiness Editor’s Note This is a compensated review for BlogHer and Intel. For the past few months, I’ve been catching myself constantly mumbling “I’m busy”. And it’s true. I’m a mom, I operate this lovely personal happiness blog called Think Simple Now, and I run a weddin photography business. All of that mixed in one bowl can be a messy combination if not stirred correctly.
Fibrinogen-like Protein 1 Is a Major Immune Inhibitory Ligand of LAG-3
Highlights • FGL1 is a major ligand of LAG-3 that mediates T cell suppression • FGL1 is normally released by the liver in low levels but by cancer in high levels • Blockade of the FGL1-LAG-3 interaction potentiates anti-tumor immunity Summary Lymphocyte-activation gene 3 (LAG-3) is an immune inhibitory receptor, with major histocompatibility complex class II (MHC-II) as a canonical ligand. However, it remains controversial whether MHC-II is solely responsible for the inhibitory function of LAG-3.
Cell Press: Cell Press
Dealing with Difficult People
Can you recall the last time you had to deal with a negative or difficult person? Or the last time someone said something with the intention of hurting you? How did you handle it? What was the result? What can you do in the future to get through these situations with peace and grace? No matter where we go, we will face people who are negative, people who oppose our ideas, people who piss us off or people who simply do not like us. There are 6.4 billion people out there and conflict is a fact of life.
Dealing with Difficult People
Can you recall the last time you had to deal with a negative or difficult person? Or the last time someone said something with the intention of hurting you? How did you handle it? What was the result? What can you do in the future to get through these situations with peace and grace? No matter where we go, we will face people who are negative, people who oppose our ideas, people who piss us off or people who simply do not like us. There are 6.4 billion people out there and conflict is a fact of life.
How to Delete Email Addiction
By Tina Su Published in productivity Photo by Stock Photo I have a secret: I am an email-holic, and I am addicted to email. Despite persistent drive to improve my productivity and personal efficiency, I am hooked on email, and occasionally social networking sites like facebook. I have read countless articles on the topic, including Tim’s 4HWW. Each time, I would get inspired, follow it for a few days, and eventually fall back on my routine of checking email, every spare moment.
Life on Purpose: 15 Questions to Discover Your Personal Mission
By Tina Su Published in happiness, motivation Photo by Thomas Hawk I believe that we were all sent here for a reason and that we all have significance in the world. I genuinely feel that we are all blessed with unique gifts. The expression of our gifts contributes to a cause greater than ourselves. First, a personal story Last year, I was running at full speed; chasing after my dream of money and ‘success’. However, I had forgotten why I was running. Luckily, I met Jim (not his real name).
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