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Keywords YAP/TAZ TEAD biomolecular condensates VGLL4 inhibitors Introduction Liquid-liquid phase separation (LLPS) has emerged as a fundamental mechanism in regulating signaling pathways.1,2,3 The evolutionarily conserved Hippo pathway that plays key roles in organ size, cell proliferation, and tumorigenesis represents one of the most studied examples in recent years.4,5,6,7 Core components of the Hippo signaling pathway consist of a kinase cascade involving mammalian STE20-like protein...
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