Tinglian Zhou

1 Introduction Dry eye disease (DED) is a multifactorial disorder characterized by disruption of tear film homeostasis, with an estimated prevalence of 5% to 50% worldwide.[1] Although DED is mainly associated with age, frequent screen use and wearing contact lenses lead to increasing diagnoses in younger people.[2, 3] Irritation, burning, mild to severe ocular inflammation, and itching eye fatigue are all characterizations of DED, which may cause potential damage to the conjunctiva, cornea,...