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Tom Rosenberg

As seen in: Nature, CINEMABLEND, Cell Reports Medicine, Forward, The 74, The Martha's Vineyard Times, Assembly Magazine
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Author Correction: A diverse landscape of FGFR alterations and co-mutations suggests potential therapeutic strategies in pediatric low-grade gliomas - Nature Communications

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By April Apfelbaum, Dominik Sturm, Georges Ayoub, Bhavyaa Chandarana, Dana Novikov, Tania Jones, Jared Collins, Kelly Cai, Hyesung Jeon, Jinhua Wang, Patrick Rechter, Karthikeyan Murugesan, Meagan Montesion, Lee A. Albacker, Philipp Sievers, Felix Sahm, Kee Kiat Yeo, Tom Rosenberg, Susan N. Chi, Steven Hebert, Alberto Picca, Valérie Larouche, Sara J. Buhrlage, Mehdi Touat, Nada Jabado, Eric S. Fischer, Olaf Witt, Claudia L. Kleinman, Denise Sheer, Keith L. Ligon
| Nature Verified
Correction to: Nature Communications https://doi.org/10.1038/s41467-025-61820-z, published online 31 July 2025 In the version of the article initially published, there were errors in the ninth paragraph of the Results, where in the text now reading “Within the DFCI and KiTZ cohorts, in which all tumors underwent review by a pediatric neuropathologist, 85% (17/20) of all FGFR1 rearrangements and/or ITDs occurred in the context of pLGGs, versus 15% (3/20) in the pHGGs,” 85% (17/20) was...
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A diverse landscape of FGFR alterations and co-mutations suggests potential therapeutic strategies in pediatric low-grade gliomas - Nature Communications

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By April Apfelbaum, Dominik Sturm, Georges Ayoub, Bhavyaa Chandarana, Tania Jones, Jared Collins, Kelly Cai, Hyesung Jeon, Jinhua Wang, Karthikeyan Murugesan, Meagan Montesion, Lee A. Albacker, Philipp Sievers, Felix Sahm, Kee Kiat Yeo, Tom Rosenberg, Susan N. Chi, Steven Hebert, Alberto Picca, Valérie Larouche, Sara J. Buhrlage, Mehdi Touat, Nada Jabado, Eric S. Fischer, Olaf Witt, Claudia L. Kleinman, Keith L. Ligon, Dana Novikov, Patrick Rechter, Denise Sheer
| Nature Verified
Abstract Oncogenic alterations in fibroblast growth factor receptor (FGFR)-family proteins occur across cancers, including pediatric gliomas. Our genomic analysis of 11,635 gliomas across ages finds that 5.3% of all gliomas harbor FGFR alterations, with an incidence of almost 9% in pediatric gliomas. Alterations in FGFR proteins are differentially enriched by age, tumor grade, and histology, with FGFR1 alterations associated with glioneuronal histologies.
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Current Open Trials and Molecular Update for Pediatric Embryonal Tumors

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By Tom Rosenberg, Tabitha M Cooney
| ncbi.nlm.nih.gov
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