Tonje Bårdsen

BDR bronchodilator reversibility BPD bronchopulmonary dysplasia BW birth weight COPD chronic obstructive pulmonary disease CPAP continuous positive airway pressure metAHR direct airway hyperresponsiveness to methacholine DLCO diffusing capacity for carbon monoxide DRS dose–response slope, the ratio of maximum percentage decline in FEV1 to cumulative administered dose methacholine EP extremely preterm, ≤28 weeks gestational age or birthweight (BW) ≤1000 g FEV1 forced expiratory volume at 1 s...

Discussion This is the first longitudinal population based study to report lung function trajectories from childhood to the mid-30s for extremely preterm-born cohorts, including also the incipient age-related physiological decline. FEV1 tracked in parallel, but significantly below the trajectories of term-born controls, including a parallel peak and onset of the age-related decline from 25 to 35 years.

Tracking of lung function from 10 to 35 years after being born extremely preterm or with extremely low birth weight Tonje Bårdsen1,2, Ola Drange Røksund1,3,4, Merete Røineland Benestad1,5, http://orcid.org/0000-0003-3170-9496Karl Ove Hufthammer6, Hege Havstad Clemm1,2, http://orcid.org/0000-0003-4192-8342Ingvild Bruun Mikalsen2,7, Knut Øymar2,7, Trond Markestad2, http://orcid.org/0000-0003-1471-0225Thomas Halvorsen1,2, Maria Vollsæter1,2 1Department of Pediatrics, Haukeland University...